C5C1N8

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
KEGG Pathway
bcv:Bcav_1246
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

534-656 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C5C1N8

Entry ID Method Resolution Chain Position Source
AF-C5C1N8-F1 Predicted AlphaFoldDB

No variants for C5C1N8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C5C1N8

No associated diseases with C5C1N8

8 regional properties for C5C1N8

Type Name Position InterPro Accession
domain Helicase, C-terminal 416 - 621 IPR001650
domain SecA DEAD-like, N-terminal 5 - 384 IPR011115
domain SecA Wing/Scaffold 614 - 828 IPR011116
domain SecA, preprotein cross-linking domain 228 - 340 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 616 IPR014018
conserved_site SecA conserved site 482 - 497 IPR020937
domain SecA, C-terminal helicase domain 402 - 586 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPSILDKVLR MGEGRILKKL TGIVAQVNAH EDTVREFTDA ELREETDVFK ARLADGETLE
70 80 90 100 110 120
AILPEAFATV REAARRTLGQ RPHDVQVMGG AALHLGNIAE MKTGEGKTLA ATLPAYLNAL
130 140 150 160 170 180
SGDGVHVVTV NDYLAQYQSD LMGRVYRFLG LTTGCILSGQ KPEERRRHYA ADITYGTNNE
190 200 210 220 230 240
LGFDYLRDNM AWSSGELVQR GHNFVIVDEV DSILIDEART PLIISGPASG DANKWYAEFA
250 260 270 280 290 300
RVARRLTRES DYEVDEKKRN VGVLEPGIEK VEDYLGIDNL YESLNTPLIG FLNNAIKAKE
310 320 330 340 350 360
LFKRDKDYVV LKGEVLIVDE HTGRILAGRR YNEGMHQAIE AKEGVAIKAE NQTLATITLQ
370 380 390 400 410 420
NYFRLYGKLA GMTGTAMTEA AEFQGTYKVG VVPIPTNMPM ARLDKPDLVF KNEDGKFDAV
430 440 450 460 470 480
VEDIVERHAA GQPVLVGTTS VEKSELLSTK LKRQGVPHEV LNAKQHAREA SIVAMAGRKG
490 500 510 520 530 540
AVTVATNMAG RGTDIMLGGN AEHLAIATLA EQGLDPNETP EEYEAAWPDA LEEATTSVAA
550 560 570 580 590 600
EHDEVVDLGG LYVLGTERHE SRRIDNQLRG RSGRQGDPGE SRFYLSMGDD LMRLFNSGLA
610 620 630 640 650 660
ERFMGSSAYP DDMPLESKLV TRGIASAQGQ VEARNFEIRK NVLKYDDVLS RQRAVIYTDR
670 680 690 700 710 720
RRVLEGEDLA EQVQGFLTDV VTAYIESATQ AGAPESWDLD ELWTALKAVY PISITPEEVV
730 740 750 760 770 780
SEAGNATRVT PEMLTREILS DAEHAYARRE EELTPDVMRQ LERRVVLAVL DRKWREHLYE
790 800 810 820 830 840
MDYLKEGIGL RAMAQRDPLV EYQREGFQLF SAMRDAIKEE AVGYLFNLEV KRPEPAESAE
850 860 870 880 890 900
ESTDGAPVVP AVPTGSDGEP LAPEQEAVPA GEPERPAKRR PAARVATRPA AEVDPLGLDT
910 920 930 940 950 960
PERPAALQYS APSSDGGSSF SEGRVVRSEG GTSGGSARPA AGASSGGGGG GANREARRRA
AKAAKKRR