C4YC37

PR
Gene name
MRI1
Protein name
Methylthioribose-1-phosphate isomerase
Names
M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Species
Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)
KEGG Pathway
clu:CLUG_05854
EC number
5.3.1.23: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

300-378 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C4YC37

Entry ID Method Resolution Chain Position Source
AF-C4YC37-F1 Predicted AlphaFoldDB

No variants for C4YC37

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C4YC37

No associated diseases with C4YC37

3 regional properties for C4YC37

Type Name Position InterPro Accession
domain Helicase, C-terminal 370 - 561 IPR001650
domain DEAD/DEAH box helicase domain 139 - 327 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 133 - 356 IPR014001

Functions

Description
EC Number 5.3.1.23 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
S-methyl-5-thioribose-1-phosphate isomerase activity Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.

2 GO annotations of biological process

Name Definition
L-methionine salvage from methylthioadenosine The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
L-methionine salvage from S-adenosylmethionine The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKDTLEAIR FDKENVTLDI LDQLLLPYES RYINIKSIQD AFEAIKSMQV RGAPAIAIVG
70 80 90 100 110 120
AFAITVDTHL YLKSGETSKT VADLLNSIDY LVTSRPTAVN LANACNEIKA LLVSHFEKSD
130 140 150 160 170 180
LVTEKVWKLL FDYSVSLHED DLRNNFKIGE NGLRFISETL KAQNFKGPFS IVTVCNTGSL
190 200 210 220 230 240
ATSGHGTALG VIRTVHAQLS KSVSNEEFWF EHVYPLETRP YNQGAKLTTY ELHYEKIPFT
250 260 270 280 290 300
MICDNMVTSL ISTLHKKKNI KGSAAPVKFI ITGADRVVKN GDSANKIGTY QLAAIADFFN
310 320 330 340 350 360
STFTKEEDKI KFMVAAPNTT IDLKTETGDE IVIEERPAHE LTSLKGPVLR EDGSVGEKMT
370 380 390 400
VGIATPGIQV WNPAFDVAPY QLIDCIVTED EPFKKVDGKF SF