C4Y9H0

PR
Gene name
CLUG_04860
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)
KEGG Pathway
clu:CLUG_04860
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C4Y9H0

Entry ID Method Resolution Chain Position Source
AF-C4Y9H0-F1 Predicted AlphaFoldDB

No variants for C4Y9H0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C4Y9H0

No associated diseases with C4Y9H0

1 regional properties for C4Y9H0

Type Name Position InterPro Accession
domain Peptidase M28 194 - 379 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRAAGCGGTG VAALTTKLSR SISQHQPKSM PQASVNSEQN PSVPNSPSAH KPARSQSAQS
70 80 90 100 110 120
APSRAKWFVR FFRSVFGYRK TSLTFLVALV FAATLLLSWA DSSLDFSVDM PTSKHEQAVL
130 140 150 160 170 180
SRSWESLQKI ARTKHTYTSE GNDEVHAYLE AHIASLVAKK PYMELDTDKN GTRRVMFDVK
190 200 210 220 230 240
YLSYDSVSYY ESNNLVVRVN GSDSSLPALL VSAHYDSVPT SYGVTDDGMG VASMLGLLEH
250 260 270 280 290 300
YSSVAQPKRT IIFNFNNNEE FGLYGAQAFL AHPWFSQIAY FLNLEGTGAG GKAILFRGTD
310 320 330 340 350 360
YGIVRHFSSV RFPFASSLFQ QGFNNRLIHS ETDYSVYIKA GLRGLDLAFY KPRDIYHTTR
370 380 390 400 410 420
DSIQNTNIKS LWHMLSSSLD FVEHVSSQTI DLDEEVHAEA GKRDLALYTS FWNHFVVFSV
430 440 450 460 470 480
SQVVSANIAL LVVVPVASLL LLFIIFRCNK GWGFNFVNAI KYPLSLVASV LVLTFVSQVI
490 500 510 520 530 540
IVPSNPFLVN SSIGLLVATL FSLFLLLNYI VLNGLNLVFK SFKGHQHDEK LIVMCESSFL
550 560 570 580 590 600
TWILLLWSTV KLSHNKFGDD HTGELFIPIL FSLQAVACFL GFLGWCFKPS KKVKVSREEH
610 620 630 640 650 660
QPLLSSNGSN YGTQDDDDSL APSSSLSLQS GFSENCEVHE TKSFSYDWLV QFLVIVPISS
670 680 690 700 710 720
LIIFNSGSLI LNGLNKSIQE SLSAQNLIYK FIQIFVIVWS IPFLPFIFKL NRIIVLALSL
730 740 750 760 770 780
VLLYGFFAVN ITDAFNDANP LKLRFLETIS MDTSPPTNLV TVSARSMDVV KDILEDMPSL
790 800 810 820 830 840
KDSKTELSID SLGDGMSLYS YETPLIPHLV PGVKNLTDYL SIDVLKDSSS VSDSPFGLLT
850 860 870 880 890 900
GELKINVPRN RNCKIDFNMS NTVIKVSDTK FMESKRSPVR TVIVYNEDKY ENKSSSVIGA
910 920 930 940 950 960
GVPEGFSRDS KGNSVFKDMD GISQLQLNKL NWDKPYHIGF QWVPEIVESE SVWSEKIRTK
970 980 990 1000 1010 1020
KLGVNIECYW GDLDQLAEKD KAGNPVVQDR VPAFEELLHY SPSYVSWANR DRGMVSVTKY
IEV