C4QYS6
Gene name |
MRI1 |
Protein name |
Methylthioribose-1-phosphate isomerase |
Names |
M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein |
Species |
Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) |
KEGG Pathway |
ppa:PAS_chr1-4_0545 |
EC number |
5.3.1.23: Interconverting aldoses and ketoses |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C4QYS6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C4QYS6-F1 | Predicted | AlphaFoldDB |
No variants for C4QYS6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C4QYS6 | |||||
No associated diseases with C4QYS6
No regional properties for C4QYS6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for C4QYS6 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 5.3.1.23 | Interconverting aldoses and ketoses |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| S-methyl-5-thioribose-1-phosphate isomerase activity | Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| L-methionine salvage from methylthioadenosine | The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine. |
| L-methionine salvage from S-adenosylmethionine | The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLQAIKFDR | QKTRLDILDQ | LLIPYQTKYI | QVSNIDDGYS | VIQKMQVRGA | PAIAIVGSFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITCELNSVKD | GQKNNHGYDV | SDLSVFKAAL | EKRIDYLIKS | RPTAVNLVNA | CTAIKAIVET |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ACTIDDLYAE | VLRYSVVLFE | DDLKNNYRIG | ANGVRYIDNE | LSNFEGPFAV | MTICNTGSLA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TSGHGTALGI | IRSLWAKSKA | NPRNADDKTI | QGQKSWLSHV | YACETRPYNQ | GSRLTSYELN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FEKIPFSLIT | DNMPAYLIDS | LFSQRVNCPL | PSRAPVKFII | VGADRIVTNG | DLANKIGTFQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LALIASQYDG | VKFIGAAPTT | TIDYTRDSGD | DIVIEQRPAN | ELTSILGGQV | DSSDQFVTDS |
| 370 | 380 | 390 | 400 | 410 | |
| EGKVNLLRIK | TATPNIDVWN | PAFDVTPNRL | IDSIVTEQDY | LVKDSHGKFN | L |