C4L8X0

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Tolumonas auensis (strain DSM 9187 / TA4)
KEGG Pathway
tau:Tola_2242
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

664-720 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C4L8X0

Entry ID Method Resolution Chain Position Source
AF-C4L8X0-F1 Predicted AlphaFoldDB

No variants for C4L8X0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C4L8X0

No associated diseases with C4L8X0

2 regional properties for C4L8X0

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 13 - 130 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 169 - 395 IPR041525

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNPIVKTFPY GQHTVTIETG VMARQATAAV MVSMDDTAVL VTVVGKKEAV EGRDFFPLTV
70 80 90 100 110 120
NYQERTYAAG RIPGGFFKRE GRPSEGETLT ARLIDRPIRP LFPEGFLNEV QVVATVMSVN
130 140 150 160 170 180
PAVSPDIVAM IGTSAALAIS GIPFNGPIGA ARVGYINDQY ILNPSVVELQ ESKLDLVVAG
190 200 210 220 230 240
TAAAVLMVES EAAILPEEVM LGAVVYGHDQ LQTVIKAVNE FAAEVGTKPW NWVAPAANVT
250 260 270 280 290 300
LKAKIAELAV AAIGEAYRIT EKAVRYDAIS ALKQRIVAEI VAADETQDAG EVADLFHELE
310 320 330 340 350 360
SDVVRGRILR GEPRIDGRDP QMIRALSVGT GVLPRVHGSA LFTRGETQAL VACTLGTERD
370 380 390 400 410 420
AQTIDEITGE RTDRFMLHYN FPPYCVGETG MMGSPKRREI GHGRLARRGV SAVIPSQAEF
430 440 450 460 470 480
PYVVRVVSEI TESNGSSSMA SVCGTSLALM DAGVPIKASV AGIAMGLVKE GDSFVVLSDI
490 500 510 520 530 540
LGDEDHLGDM DFKVAGTSEG VTALQMDIKI EGITKEIMQI ALKQARDARL HILTVMDKAI
550 560 570 580 590 600
GVARDDISDF APRIHTIKIN PEKIKDVIGK GGSVIRALTE ETGTTIELED DGTVKIAAVS
610 620 630 640 650 660
GEAAQEAIRR IQALTADVEI GRIYEGKVTR LAEFGAFVNI LPGKDGLVHI SQITDERVKD
670 680 690 700 710
VSDYLKVGDM VRTKVLEVDR QGRIRLSIKE AKRDELPAAE SVAESAPAQE AVVEQVPMTE