Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for C4K3F0

Entry ID Method Resolution Chain Position Source
AF-C4K3F0-F1 Predicted AlphaFoldDB

No variants for C4K3F0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C4K3F0

No associated diseases with C4K3F0

7 regional properties for C4K3F0

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 382 - 551 IPR000795
domain Small GTP-binding protein domain 385 - 541 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 307 - 357 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 58 - 94 IPR013575
domain Translation initiation factor IF- 2, domain 3 658 - 772 IPR023115
domain Translation initiation factor IF-2, domain II 558 - 651 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTVKSLA EEIKTSVDRL VQQFFDAGIK KSQTDTVTQQ EKEKLLAHLN RQQGTVDNQL
70 80 90 100 110 120
TLQRKTRSVL NIQVTGGKSK TVHIEVRKKR TYVNPSVTKP EAPLPEEENA QIPKITKNTF
130 140 150 160 170 180
SQESLNKTSP QKSLKTKAIE KAKIESPKKE RHSLKEKQKK EAQSEKARRE AEASSLKRFA
190 200 210 220 230 240
EEEVRRKVEE EAKRVAEQAR KMAIENEAKW SELVADQIDS VDYHVTTSEH ARAAEDENDA
250 260 270 280 290 300
KVEGDRRSRH RGTKTTKQKK TNKLSESKTD REEARAVVRK SKRKPSALQQ SFNKPVVALN
310 320 330 340 350 360
RDVVIGETIS VAELANKMAV KGSQVIKAMM KLGAMATINQ VIDQETAQLV AEEMGHKVIL
370 380 390 400 410 420
RRENELEEAL MSDRDTGVLT VHRAPVVTIM GHVDHGKTSL LDYIRSTKVA TGEAGGITQH
430 440 450 460 470 480
IGAYHVETEN GMITFLDTPG HAAFTSMRAR GAQATDIVVL VVAADDGVMP QTIEAIQHAK
490 500 510 520 530 540
AAKVPVVVAV NKIDKAEADP DRVKKELIQH GIQPEEWGGD SQFIHVSAKV GTGIDDLLNA
550 560 570 580 590 600
ILLQAEVLEL KAVKSGMANG VVIESFLDKG RGPVATVLVQ EGTLNKGDIV LCGFQYGRVR
610 620 630 640 650 660
AMRNELGREV ISAGPSIPVE ILGLSSVSSA GDAVTVVRDE KKAREVALYR QGKFREIKLA
670 680 690 700 710 720
RQQKSKLENM FDSLREGEIS ELNIVLKSDV QGSCEAIREA LQKLSTDEVK IKIIGSGVGG
730 740 750 760 770 780
ITETDATLAA ASNAIILGFN VRADAATRRL VEAENLNLRY YSVIYDLLDE VKQAMSGMLS
790 800 810 820 830 840
PKYEQKIIGL AEVRDVFKSP KFGAIAGCMV VEGLIKRSSP IRVLRNNVVI YEGELESLRR
850 860 870 880
FKDDVNEVRN GIECGIGVKN YDVQVNDTIE VFEIIEIKRT IS