C3KCS9

PR
Gene name
ftsW
Protein name
Probable peptidoglycan glycosyltransferase FtsW
Names
PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase
Species
Pseudomonas fluorescens (strain SBW25)
KEGG Pathway
pfs:PFLU_0946
EC number
2.4.1.129: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

353-407 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C3KCS9

Entry ID Method Resolution Chain Position Source
AF-C3KCS9-F1 Predicted AlphaFoldDB

No variants for C3KCS9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C3KCS9

No associated diseases with C3KCS9

1 regional properties for C3KCS9

Type Name Position InterPro Accession
conserved_site Cell cycle, FtsW / RodA / SpoVE, conserved site 341 - 365 IPR018365

Functions

Description
EC Number 2.4.1.129 Hexosyltransferases
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
  • Localizes to the division septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
peptidoglycan glycosyltransferase activity Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.

4 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
regulation of cell shape Any process that modulates the surface configuration of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSIDFRNIIK PYPSPIITGR GIDLDFPMLA GCLALLGLGL VMITSASSEV AAVQSGNTLY
70 80 90 100 110 120
MMIRHLVYLV IGLGACIVTM MIPIATWQRL GWLMLIGAFG LLIMVILPGI GREVNGSMRW
130 140 150 160 170 180
IGFGAFNVQP SEIAKVFVVI YLAGYLVRRQ KEVRESWMGF FKPFIVLLPM AGLLLMEPDF
190 200 210 220 230 240
GATVVMMGAA AAMLFLGGVG LFRFTLMVVL AVAAVTVLVQ AQPYRMARLI TFTDPWSDQF
250 260 270 280 290 300
GSGYQLTQAL IAFGRGEWLG VGLGNSVQKQ FYLPEAHTDF VFSVLAEELG VVGSLCTVAL
310 320 330 340 350 360
FVFVCVRGMY IGMWAEKAKQ YFAAYVAYGL SFLWIGQFLI NIGVNVGLLP TKGLTLPFLS
370 380 390 400
YGGSSLVICC ACLGLLLRIE WESRTHLGSE EMEFSESDFA EEPTHGR