C1KZZ5

PR
Gene name
isdG
Protein name
Heme-degrading monooxygenase
Names
Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant
Species
Listeria monocytogenes serotype 4b (strain CLIP80459)
KEGG Pathway
lmc:Lm4b_00504
EC number
1.14.14.18: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

24-121 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1KZZ5

Entry ID Method Resolution Chain Position Source
AF-C1KZZ5-F1 Predicted AlphaFoldDB

No variants for C1KZZ5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1KZZ5

No associated diseases with C1KZZ5

1 regional properties for C1KZZ5

Type Name Position InterPro Accession
domain Antibiotic biosynthesis monooxygenase domain 1 - 101 IPR007138

Functions

Description
EC Number 1.14.14.18 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
heme oxygenase (decyclizing) activity Catalysis of the reaction: heme b + 3 O2 + 3 reduced
iron ion binding Binding to an iron (Fe) ion.

2 GO annotations of biological process

Name Definition
heme catabolic process The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
iron import into cell The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIIVTNTIKV EKGAAEHVIR QFTGANGDGH PTKDIAEVEG FLGFELWHSK PEDKDYEEVV
70 80 90 100 110 120
VTSKWESEEA QRNWVKSDSF KKAHGRTKDT REQREDRKGI VGNAIARFEV VHVQNPVIVE
K