C1I202

PR
Gene name
pnpB
Protein name
p-benzoquinone reductase
Names
NAD(P)H dehydrogenase (quinone)
Species
Pseudomonas sp (strain WBC-3)
KEGG Pathway
ag:ABU50909
EC number
1.6.5.6: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

86-207 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for C1I202

Entry ID Method Resolution Chain Position Source
4LA4 X-ray 207 A A/B 1-207 PDB
4LAF X-ray 176 A A/B/C/D 1-207 PDB
AF-C1I202-F1 Predicted AlphaFoldDB

No variants for C1I202

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1I202

No associated diseases with C1I202

4 regional properties for C1I202

Type Name Position InterPro Accession
domain DNA-directed DNA polymerase, family B, exonuclease domain 29 - 194 IPR006133-1
domain DNA-directed DNA polymerase, family B, exonuclease domain 197 - 291 IPR006133-2
domain DNA-directed DNA polymerase, family B, multifunctional domain 357 - 759 IPR006134
conserved_site DNA-directed DNA polymerase, family B, conserved site 543 - 551 IPR017964

Functions

Description
EC Number 1.6.5.6 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

6 GO annotations of molecular function

Name Definition
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
FMN binding Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
NAD(P)H dehydrogenase (quinone) activity Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
NADP binding Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
p-benzoquinone reductase (NADPH) activity Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+).

2 GO annotations of biological process

Name Definition
4-nitrophenol catabolic process The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
aromatic compound catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPTKIQIVFY SSYGHIYKMA EAIAAGAREV GDVEVTLLQV PELMPEEVQV KSGIKGYRAA
70 80 90 100 110 120
FGSIPYATPE VLAEADAIIF GTPTRFGNMC SQMRNFLDQT GGLWMSGGLI GKVGSVFTST
130 140 150 160 170 180
ASQHGGQETT ITSFHTTLLH HGMVIVGVPY SEPGLTNMTE ISGGTPYGAS TLAGADGSRQ
190 200
PSENELQIAR FQGKHVATIA KRLANNK