C1HE31
Gene name |
ECM14 (PAAG_09024) |
Protein name |
Inactive metallocarboxypeptidase ECM14 |
Names |
|
Species |
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis) |
KEGG Pathway |
pbl:PAAG_09024 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C1HE31
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C1HE31-F1 | Predicted | AlphaFoldDB |
No variants for C1HE31
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C1HE31 | |||||
No associated diseases with C1HE31
1 regional properties for C1HE31
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Peptidase M14, carboxypeptidase A | 204 - 514 | IPR000834 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRLFARLEVL | AILACAVPIA | AIPSFLSNSY | PAHPAEGVSL | FPQTQPQAPL | GLWTRLRNTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IERLWRVPPQ | LNKNRPGKQG | KFPLFSAPVS | LRARYGDDVV | LRFTIRNAEE | VKALAEASNI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LFLDVWASTD | EWVDIRLTKD | VVPSLLGLLP | QSLQTSHIPL | IHDLPQTIYE | SYPSSSQRSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YDVQGFSPST | KHSSDITNIF | FQDYQPFSVI | VTWMRFLTSM | FSSHVQIINI | GSTFEGRDIP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ALQIGVWPAN | NPKPRKTVVV | SGGSHAREWI | SVSTVNYVAY | SLITSYAKSK | HVAELLQQFD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FIFIPTLNPD | GYIYTWEVDR | IWRKNRQETS | LPFCPGVDLD | RTWGFEWDGN | ITADNPCSES |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YPGEDPFAGV | EAKQFSQWAK | NQTAQNNIEF | VAFIDLHSYS | QQIRYPYSYS | CLPNPPNLEN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LEELAIGIAK | AIRLTNRETY | EVSSACEGFM | ASQAKAKSDD | PFPRIERTGG | SALDWFYHDL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NVKYSYQIKL | RDRGSYGFLL | PRENIVPTGQ | EMFNAVMVLG | RFLSGHDGFG | HLDWEDESQR |
| 550 | 560 | 570 | 580 | 590 | |
| PKADEDDIPS | ENELGENDDS | WIPFDYRNHD | DQNEGEGYDN | DEWGFRRRRK | G |