C1GTI3

PR
Gene name
PAAG_01828
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides brasiliensis)
KEGG Pathway
pbl:PAAG_01828
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

551-636 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1GTI3

Entry ID Method Resolution Chain Position Source
AF-C1GTI3-F1 Predicted AlphaFoldDB

No variants for C1GTI3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1GTI3

No associated diseases with C1GTI3

1 regional properties for C1GTI3

Type Name Position InterPro Accession
domain Peptidase M28 165 - 343 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPAMANPRV RKFNPIAFTP LPVTLITTIV YLAVLILVLV TYLVVPPAPT LEMSPRGVNL
70 80 90 100 110 120
TEAWRDLQHL TGGFHPYNSR RNDDVHAWLL HRIEAIVREH SAAADDVPEV FVFDDNLSNL
130 140 150 160 170 180
TYSNGGVSKS PIVGVYFEST NIIVYIRGSE DDPQNWWEWS NGKPKGKGGV LVNAHYDSVS
190 200 210 220 230 240
TGYGATDDGM GVVSLLQLLR YFTIAGNKPR KGLVLLFNNG EEDYLNGARV YSQHAMSNFT
250 260 270 280 290 300
HTFLNLEGAG AGGRACLFRT TDTEVTRFYK NAKHPFGSVL AGDGFKLGLI RSQTDYVVFN
310 320 330 340 350 360
GVLGLRGLDV SFIAPRSRYH TDQDDARHTN VDSLWHMLSV AIATTEGLVS YTGTDFDSKT
370 380 390 400 410 420
TDQDKVNSGD GTLGVWFDIF GSAFAVFRLH TLFALSVTLL VSAPLVLFIT SIALSKTDRM
430 440 450 460 470 480
YLFSMSKSLG GTSETVSLRG LRGLFRTPII LTVTTVITIG LAYLLEKINP YIVHSSQFAV
490 500 510 520 530 540
WSMMLSVWIF VAWFLARVAD FFRPSALHRA YSYTWIFIAT WIMLVISTVY ANQKGIAAGY
550 560 570 580 590 600
FIFFYFAAVF LATWVSYLEL FSLPRKGYYA HQTSRGQRRR SSSLSSRLLT PSADELPSDI
610 620 630 640 650 660
GPNGAENLGD PDETDPTEST SLLRGQRTTF ANYRTGGNSG VTEYTAEGEH VREAGIFGHE
670 680 690 700 710 720
QSWSWTLPRW TWILQLLLLA PIVIILVGQV GLLLTTAMSQ IGSDGVSTFI VYLACALLST
730 740 750 760 770 780
LLFAPLFPFI HRFTYHVPTF LLLIFIGTLI YNLVAFPFSP ANRLKIFFIQ EVNLDDGTNK
790 800 810 820 830 840
VSLTGIQPYL TNTINAIPSA AGQTANCTQG PFGSLVRCSW SGPPPRVVKE DPGNDQTMGP
850 860 870 880 890 900
YTWISYNITK TVGKNEARIK VSGRNTRACK LKFDNPVADY RISGSAVDHR LPHTSRQGVA
910 920 930 940 950 960
EIRLWSRTWE NTWVVDVDWH SNPVKPGESK DGDEKQDVSK NELSGKVICL WSDNNESGVI
970 980 990
PALDEVRLYA PAWVAISKSA DGLVEASHDF IIQ