C1G0X0

PR
Gene name
PADG_00510
Protein name
Vacuolar membrane protease
Names
FXNA-related family protease 1
Species
Paracoccidioides brasiliensis (strain Pb18)
KEGG Pathway
pbn:PADG_00510
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

543-639 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1G0X0

Entry ID Method Resolution Chain Position Source
AF-C1G0X0-F1 Predicted AlphaFoldDB

No variants for C1G0X0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1G0X0

No associated diseases with C1G0X0

1 regional properties for C1G0X0

Type Name Position InterPro Accession
domain Peptidase M28 164 - 340 IPR007484

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloexopeptidase activity Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPAMANPRV RKFNPIAFTP LPVTFITTIV YLAVLILVLV TYLVVPPAPT LEMSPKGVNL
70 80 90 100 110 120
TEAWRDLQHL TEGFHPYNSR RNDDVHAWLL HRIEAIVRES AAADGGPEVF VFDDNLSNLT
130 140 150 160 170 180
YSNGGVSKSP IVGVYFESTN IIVYIRGSED DPQNWWEWSN GKPKGKGGVL VNAHYDSVST
190 200 210 220 230 240
GYGATDDGMG VVSLLQLLRY FTTAGNKPRK GLVLLFNNGE EDYLNGARVY SQHAMSNFTH
250 260 270 280 290 300
TFLNLEGAGA GGRACLFRST DTEVTRFYKN AKHPFGSVLA GDGFKLGLIR SQTDYVVFNG
310 320 330 340 350 360
VLGLRGLDVS FIAPRSRYHT DQDDARHTNV DSLWHMLSVA IGTTEGLVSY TGTDFDSKTT
370 380 390 400 410 420
DQDKVNSGGG TLGVWFDIFG SAFAVFRLHT LFALSVTLLV IGPLVLFITS IALSKTDRMY
430 440 450 460 470 480
LFSMSKSLGG ASETVSLRGL RGLFRTPIIL TVTTVISIGL AYLLEKINPY IVHSSQFAVW
490 500 510 520 530 540
SMMLSVWIFV AWFLARVADF FRPSALHRAY SYTWIFIVTW IMLVISTVYA NQKGIAAGYF
550 560 570 580 590 600
TFFYFAAVFL ATWVSYLELF SLPRKGYYAR QASRRQRRRS SSLSSRLLTP SADELPSDIG
610 620 630 640 650 660
PNGAENVGDP DETDPTESTS LLRGQRTTFA NYRTGGDDGV TEYTAEDEHV REASIFGHEQ
670 680 690 700 710 720
SWSWTLPRWT WILQLLLLAP IVIILVGQVG LLLTTAMSQI GSDGVSTFIV YLACALFSTL
730 740 750 760 770 780
LFAPLLPFIH RFTYHVPIFL LLIFIGTLIY NLVAFPFSPA NRLKIFFIQE VNLDDGTNKV
790 800 810 820 830 840
SLTGIQPYLT DTINAIPSAA GQTANCTQGP FGSLVRCSWS GLPPRVVKED PGNDQTMGPY
850 860 870 880 890 900
TWISYNITRT VGKNEARIKV SGRNTRACKL KFDNPVADYR ISGSAVDHRL PHTSRQGVEE
910 920 930 940 950 960
IRLWTRTWEN TWVVDVDWHS NPVNPGESKD GDEKQDVSKN ELSGKVICLW SDNNESGVIP
970 980 990
ALDEVRLYAP AWVAISKSAD GLVEASHDFI IQ