C1FS59

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Clostridium botulinum (strain Kyoto / Type A2)
KEGG Pathway
cby:CLM_2711
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-214 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1FS59

Entry ID Method Resolution Chain Position Source
AF-C1FS59-F1 Predicted AlphaFoldDB

No variants for C1FS59

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1FS59

No associated diseases with C1FS59

6 regional properties for C1FS59

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 187 - 354 IPR000795
domain Small GTP-binding protein domain 191 - 346 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 49 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 110 - 158 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 464 - 577 IPR023115
domain Translation initiation factor IF-2, domain II 362 - 457 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKIRVYELA KELNISSKEL ITLLEEEFSV EVKNHMSAIE DEDANLIKEL LSGKEKSEKT
70 80 90 100 110 120
KEEDDEIETT AKNPIKESMN NKKSNKRDDK NEKVNTENAE DMGIITMTSD TITVKEISDK
130 140 150 160 170 180
LEKSYAEVIK ELMLMGVMAS VNQEINFEMA EKLAAKFDME ILKEDEDEKE DLEDILKDNE
190 200 210 220 230 240
EEEYLQKRSP IITVMGHVDH GKTSLLDAIR KSKITSTEAG GITQHIGAYT VELNGEAITF
250 260 270 280 290 300
LDTPGHAAFT AMRARGAQVT DIVILVVAAD DGIMPQTQEA ISHCKAANVP LIVAINKIDR
310 320 330 340 350 360
PGANIDKVKQ ELTEYGLVAE DWGGDTICVP VSAHTKEGID DLLEMILLSS EILELKANPN
370 380 390 400 410 420
RKAKGTVVEA KLDKGRGPVA TLLIQNGTLR VGDSIVVGST YGRIRAMFND KGRNIESAGP
430 440 450 460 470 480
STPVEILGLS EVPEAGDKFY QVKEEKTARG IADKRKEKIR DEYLQSTHKV SLEDLYNQIQ
490 500 510 520 530 540
EGTVKELGLI VKADVQGSVE ALKQSLEKLS TEEVKVRVIH GGVGAINETD VTLATASNGI
550 560 570 580 590 600
ILGFNVRPDN NAIIASERDG VDIKTYRVIY DAIEDIKSAM LGMLEPEFKE VVIGTAEVRQ
610 620 630 640 650 660
VYKISSVGTI AGAYIQTGKL ARNAGARVIR DGIVIFESEL ASLKRFKDDA KEVAQGYECG
670 680
LSIEKFNDIK EGDIIECFIM EEIKKKTL