C1DUY4

PR
Gene name
hemL
Protein name
Glutamate-1-semialdehyde 2,1-aminomutase
Names
GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT
Species
Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825)
KEGG Pathway
saf:SULAZ_0948
EC number
5.4.3.8: Transferring amino groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

122-199 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1DUY4

Entry ID Method Resolution Chain Position Source
AF-C1DUY4-F1 Predicted AlphaFoldDB

No variants for C1DUY4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1DUY4

No associated diseases with C1DUY4

No regional properties for C1DUY4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for C1DUY4

Functions

Description
EC Number 5.4.3.8 Transferring amino groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
glutamate-1-semialdehyde 2,1-aminomutase activity Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
transaminase activity Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.

1 GO annotations of biological process

Name Definition
protoporphyrinogen IX biosynthetic process The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNILKSKELF KEAQNYLVGG VNSPVRAFKA VGTDPIFIQR GKGSRIWDVD GNEYIDYVLS
70 80 90 100 110 120
WGPLILGHAH DQVVNAIKQV ANYGTSFGAP TELEIEMAKA VVDAVKSVEM VRFVNSGTEA
130 140 150 160 170 180
TMSAIRLARG YTKRKKIVKF DGCYHGHGDS LLVSAGSGVA TLGIPGTPGI PEELANLTIV
190 200 210 220 230 240
LPYNDIEAVE EAFKRYGEDI ACVIIEPVAG NMGVVAPSKE YHQRLRDITR KYGALLIFDE
250 260 270 280 290 300
VMTGFRLAYG GAQELYGIDP DLTTFGKVIG GGLPVGAYGG KREIMEYVAP VGPVYQAGTL
310 320 330 340 350 360
SGNPLAMAAG LRQLQLLKEL NPYRELDEKG RFLEEGFKQI AQEFSAAIQV NRVGSMITVF
370 380 390 400 410 420
FTDIPVKDFA TAKTSDTNKF AKFFRCMLEK GIYLPASQFE AFFLSTAHSQ KDLEETLEKA
RECFKIL