C1CXR4

PR
Gene name
carB
Protein name
Carbamoyl-phosphate synthase large chain
Names
Carbamoyl-phosphate synthetase ammonia chain
Species
Deinococcus deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)
KEGG Pathway
ddr:Deide_00700
EC number
6.3.4.16: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

627-707 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1CXR4

Entry ID Method Resolution Chain Position Source
AF-C1CXR4-F1 Predicted AlphaFoldDB

No variants for C1CXR4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1CXR4

No associated diseases with C1CXR4

13 regional properties for C1CXR4

Type Name Position InterPro Accession
domain Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 128 - 334 IPR005479-1
domain Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 666 - 869 IPR005479-2
domain Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 417 - 540 IPR005480
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 19 - 33 IPR005483-1
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 48 - 58 IPR005483-2
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 168 - 180 IPR005483-3
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 204 - 223 IPR005483-4
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 239 - 256 IPR005483-5
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 297 - 326 IPR005483-6
domain Carbamoyl-phosphate synthase large subunit, CPSase domain 379 - 397 IPR005483-7
domain Methylglyoxal synthase-like domain 930 - 1028 IPR011607
domain ATP-grasp fold 133 - 328 IPR011761-1
domain ATP-grasp fold 671 - 863 IPR011761-2

Functions

Description
EC Number 6.3.4.16 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKRTDLQTI LILGSGPIQI GQAAEFDYSG TQALKALRGE GYRVVLVNSN PATIMTDPDL
70 80 90 100 110 120
ADATYLEPLT PEFVEKIIAL EKPDAILPTL GGQTALNLAM ELHERGTLEK YGVELIGAGV
130 140 150 160 170 180
EAIKKGEDRE LFQAAMKKIG VETARGKMVH SMEEAVEYQK EIGLPIVIRP SFTLGGTGGG
190 200 210 220 230 240
IAHTYEEFLA ITEGGLRDSP VTSVLLEESI LGWKEYELEV MRDTADTVII ITSIENFDPM
250 260 270 280 290 300
GVHTGDSITV APAQTLSDVE YQRLRNQSLA IIREIGVATG GSNIQFAVNP DNGRVIVIEM
310 320 330 340 350 360
NPRVSRSSAL ASKATGFPIA KIAALLAVGY HLDELPNDIT RVTPASFEPS IDYVVTKIPR
370 380 390 400 410 420
FAFEKFPGTS DHLGTQMRSV GEVMAIGRTF KESLQKALRS TESDIRGVYA EMDEAGLRAL
430 440 450 460 470 480
LYPNPRRIEA VIELLRRGES IDALFDATKI DRWFLEQIKE IIDAEHELLE LGPISEWKYE
490 500 510 520 530 540
YWREVKRLGF SDARIGEIVG LSELQVRQLR KAARATPVYK TVDTCAAEFE AYTPYHYSTY
550 560 570 580 590 600
EWEDEVTGTD KPKVVILGSG PNRIGQGVEF DYATVHAVWA LQEAGYETIM VNSNPETVST
610 620 630 640 650 660
DYDTADRLYF EPLTFEDVMN IVDHEKPVGV IVQLGGQTPL KLAKKLADAG APIIGTSPET
670 680 690 700 710 720
IHEAEDRASF NALCERLGLS QPRGKVAETP EQARQLAAEL GFPLMARPSY VLGGRAMRTV
730 740 750 760 770 780
RSMEELVTYL DEVYAAVEGQ PSILLDQFLE GALELDVDTL CDGERAVVAG IMEHVEAAGV
790 800 810 820 830 840
HSGDSACVLP PVNLSAELLA RVKADTERLA LELGVRGLMN VQWAVKDGTA YILEANPRAS
850 860 870 880 890 900
RTVPFVSKAV NHPLAKSAAR IAVGHTLEQI GLTETPEAAM YSVKEVHLPF LKFKGVSPIL
910 920 930 940 950 960
GPEMKSTGES MGIDADPYLA FYRAQLGAKS YLPLSGTALL LGDGLDEVAS TLQGAGLNVI
970 980 990 1000 1010 1020
REQDGNTLPD LLIDVTGSPL LRTALERGVP IVSTREAAVW TSKAIAAAQG SELRVRSLQD
WQTQEAVAG