C1CAC7

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Streptococcus pneumoniae (strain 70585)
KEGG Pathway
snm:SP70585_0178
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

411-463 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1CAC7

Entry ID Method Resolution Chain Position Source
AF-C1CAC7-F1 Predicted AlphaFoldDB

No variants for C1CAC7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1CAC7

No associated diseases with C1CAC7

3 regional properties for C1CAC7

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 279 - 288 IPR020557
domain Fumarate lyase, N-terminal 10 - 304 IPR022761
domain Argininosuccinate lyase, C-terminal 367 - 434 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKNTKLWGG RFEGTVEDWV ERFGASISFD QKLAKFDVIG SLAHVQMLGQ TGILSLEESE
70 80 90 100 110 120
KIQVGLKELL EELEAGQLDF DIANEDIHMN MEVLLTEKIG PLAGKLHTAR SRNDQVATDM
130 140 150 160 170 180
HLYLKEQLGY VLDKLAHLKG VLLDLAENHV ATIMPGYTHL QHAQPISFAH HLMAYYNMFQ
190 200 210 220 230 240
RDSERFEFNQ KHTDLCPLGA AALAGTTFPI DRQLSSDLLE FKQPYTNSLD AVSDRDFILE
250 260 270 280 290 300
FLSNASILMM HMSRFCEEMI NWCSFEYQFI TLSDTFTIGS SIMPQKKNPD MAELIRGKTG
310 320 330 340 350 360
RVYGHLFGLL TVMKSLPLAY NKDLQEDKEG MFDTVETILN SLDVLAGMLS SLQVNKEKMQ
370 380 390 400 410 420
ESTEKDFSNA TELADYLAGK GLPFREAHEV VGRLVLDSIK SAKNLQDWTL EELQTYHSLI
430 440 450 460
TEDIYVYLQP KTAVQRRNSL GGTGFDQVEY QIAVAKKANE AKK