C1C6Y4

PR
Gene name
pepT
Protein name
Peptidase T
Names
Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase
Species
Streptococcus pneumoniae (strain 70585)
KEGG Pathway
snm:SP70585_1047
EC number
3.4.11.4: Aminopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-59 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C1C6Y4

Entry ID Method Resolution Chain Position Source
AF-C1C6Y4-F1 Predicted AlphaFoldDB

No variants for C1C6Y4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C1C6Y4

No associated diseases with C1C6Y4

2 regional properties for C1C6Y4

Type Name Position InterPro Accession
domain eRF1 domain 1/Pelota-like 1 - 123 IPR005140
domain eRF1 domain 3 245 - 341 IPR005142

Functions

Description
EC Number 3.4.11.4 Aminopeptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
tripeptide aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
peptide catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTYPNLLDRF LTYVKVNTRS DEHSTTTPST QSQVDFATNV LIPEMKRVGL QNVYYLPNGF
70 80 90 100 110 120
AIGTLPANDP SLTRKIGFIS HMDTADFNAE GVNPQVIENY DGGVIELGNS GFKLDPADFK
130 140 150 160 170 180
SLEKYPGQTL ITTDGTSLLG ADDKSGIAEI MTAIEYLTAH PEIKHCEIRV GFGPDEEIGV
190 200 210 220 230 240
GANKFDAEDF DVDFAYTVDG GPLGELQYET FSAAGAELHF QGRNVHPGTA KGQMVNALQL
250 260 270 280 290 300
AIDFHNQLPE NDRPELTEGY QGFYHLMDVT GSVEEARASY IIRDFEKDAF EARKASMQSI
310 320 330 340 350 360
ADKMNEELGS DRVTLNLTDQ YYNMKEVIEK DMTPITIAKA VMEDLGITPI IEPIRGGTDG
370 380 390 400
SKISFMGIPT PNIFAGGENM HGRFEYVSLQ TMERAVDTII GIVAYKG