C0ZFA5

PR
Gene name
codY
Protein name
GTP-sensing transcriptional pleiotropic repressor CodY
Names
Species
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
KEGG Pathway
bbe:BBR47_34870
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

29-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for C0ZFA5

Entry ID Method Resolution Chain Position Source
AF-C0ZFA5-F1 Predicted AlphaFoldDB

No variants for C0ZFA5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for C0ZFA5

No associated diseases with C0ZFA5

2 regional properties for C0ZFA5

Type Name Position InterPro Accession
domain Global transcriptional regulator CodY, N-terminal 3 - 178 IPR010312
domain Global transcriptional regulator CodY, C-terminal 198 - 255 IPR013198

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
GTP binding Binding to GTP, guanosine triphosphate.

1 GO annotations of biological process

Name Definition
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDLLSKTRRI NRMLQKSAGH AVNFNEMSQV LSDVIEANTY VVSRKGKLLG FAIHQEMDNS
70 80 90 100 110 120
RMRKMLEDRR FPEEYSMGLL KVDETSANLD VDSPYTIFPV EMKEVFRTGW TTLVPIMGGG
130 140 150 160 170 180
DRLGTLILGR INDQFVDDDL ILAEVGATVV GMEILRERSE AIEEEARSKA VVQMAIGSLS
190 200 210 220 230 240
YSELEAVEHI FEELEGKEGL LVASKIADRV GITRSVIVNA LRKLESAGVI ESRSLGMKGT
250
FIKVLNEKLL PELEKLKTS