C0SVV6
Gene name |
CBP60A |
Protein name |
Calmodulin-binding protein 60 A |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G62570 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C0SVV6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C0SVV6-F1 | Predicted | AlphaFoldDB |
41 variants for C0SVV6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH03465036 | 4 | P>L | No | 1000Genomes | |
| ENSVATH03465037 | 9 | G>R | No | 1000Genomes | |
| ENSVATH03465038 | 24 | V>I | No | 1000Genomes | |
| tmp_5_25115370_G_A | 88 | R>Q | No | 1000Genomes | |
| tmp_5_25115426_G_T | 107 | G>C | No | 1000Genomes | |
| ENSVATH12907834 | 109 | I>V | No | 1000Genomes | |
| ENSVATH12907836 | 110 | F>L | No | 1000Genomes | |
| ENSVATH12907835 | 110 | F>V | No | 1000Genomes | |
| ENSVATH07468315 | 119 | K>T | No | 1000Genomes | |
| tmp_5_25115485_G_T | 126 | E>D | No | 1000Genomes | |
| tmp_5_25115483_G_A | 126 | E>K | No | 1000Genomes | |
| tmp_5_25115493_T_G | 129 | F>C | No | 1000Genomes | |
| tmp_5_25115498_A_T | 131 | S>C | No | 1000Genomes | |
| ENSVATH07468316 | 141 | R>K | No | 1000Genomes | |
| tmp_5_25115544_G_A | 146 | R>K | No | 1000Genomes | |
| ENSVATH03465041 | 149 | E>K | No | 1000Genomes | |
| ENSVATH12907839 | 156 | N>S | No | 1000Genomes | |
| ENSVATH00748108 | 159 | V>I | No | 1000Genomes | |
| tmp_5_25115591_G_A | 162 | V>I | No | 1000Genomes | |
| ENSVATH03465042 | 200 | V>I | No | 1000Genomes | |
| ENSVATH03465043 | 209 | S>C | No | 1000Genomes | |
| ENSVATH03465046 | 251 | S>A | No | 1000Genomes | |
| ENSVATH03465046 | 251 | S>T | No | 1000Genomes | |
| ENSVATH07468320 | 255 | T>N | No | 1000Genomes | |
| ENSVATH07468321 | 256 | V>L | No | 1000Genomes | |
| tmp_5_25116281_G_A | 294 | V>I | No | 1000Genomes | |
| ENSVATH07468324 | 313 | V>I | No | 1000Genomes | |
| ENSVATH03465047 | 335 | K>T | No | 1000Genomes | |
| tmp_5_25116423_A_G | 341 | K>R | No | 1000Genomes | |
| ENSVATH00748109 | 342 | A>S | No | 1000Genomes | |
| tmp_5_25116567_A_C | 362 | D>A | No | 1000Genomes | |
| ENSVATH03465048 | 380 | S>N | No | 1000Genomes | |
| ENSVATH00748110 | 382 | A>P | No | 1000Genomes | |
| ENSVATH03465049 | 391 | L>F | No | 1000Genomes | |
| ENSVATH12907877 | 413 | H>Y | No | 1000Genomes | |
| ENSVATH12907878 | 414 | S>R | No | 1000Genomes | |
| ENSVATH15247714 | 418 | D>G | No | 1000Genomes | |
| ENSVATH12907879 | 442 | L>I | No | 1000Genomes | |
| ENSVATH07468326 | 447 | S>F | No | 1000Genomes | |
| ENSVATH12907880 | 451 | S>N | No | 1000Genomes | |
| tmp_5_25116866_G_A | 462 | A>T | No | 1000Genomes |
No associated diseases with C0SVV6
1 regional properties for C0SVV6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, CCCH-type | 535 - 562 | IPR000571 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of defense response to bacterium | Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. |
| regulation of salicylic acid biosynthetic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRIPTYDFGS | KFSVVQEVMR | LQTVKHFLEP | VLEPLIRKVV | KEEVELALGK | HLAGIKWICE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KETHPLESRN | LQLKFLNNLS | LPVFTSARIE | GDEGQAIRVG | LIDPSTGQIF | SSGPASSAKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EVFVVEGDFN | SVSDWTDEDI | RNNIVREREG | KKPLLNGNVF | AVLNDGIGVM | DEISFTDNSS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WTRSRKFRLG | VRIVDQFDYV | KIREAITESF | VVRDHRGELY | KKHHPPSLFD | EVWRLEKIGK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DGAFHRRLNL | SNINTVKDFL | THFHLNSSKL | RQVLGTGMSS | KMWEITLDHA | RSCVLDSSVH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VYQAPGFQKK | TAVVFNVVAQ | VLGLLVDFQY | IPAEKLSEIE | KAQAEVMVID | ALSHLNEVIS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YDDEVSMMRN | VLNAPASQGS | VAGIDYSGLS | LTSLDGYGFV | SSLHNTAECS | GKHSDDVDME |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VTPHGLYEDY | DNLWNCSHIL | GLEEPQSELQ | SALDDFMSQK | NASVGGKAHS | KRWTKLFSVS |
| 490 | |||||
| RWLSVFKYVK | LGKI |