C0SJS4
Gene name |
CYP71AJ2 |
Protein name |
Psoralen synthase |
Names |
Cytochrome P450 CYP71AJ2 |
Species |
Apium graveolens (Celery) |
KEGG Pathway |
|
EC number |
1.14.14.141: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C0SJS4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C0SJS4-F1 | Predicted | AlphaFoldDB |
No variants for C0SJS4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C0SJS4 | |||||
No associated diseases with C0SJS4
1 regional properties for C0SJS4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 422 - 431 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.141 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| psoralen synthase activity | Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| YFFSLFLVTV | FVYKLLTLKK | TPSKNLPPSP | PRYPIIGNLH | QIGPDPQHSL | RDLALKYGPL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MSLKFGTVPV | LVVSSADAAR | EVLKTHDLIF | ADRPYSSVAN | KVFYNGKDMV | FARYTEYWRQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VKSICVTQLL | SNKRVNSFQN | VREEEVDLLV | QNIENSCSKV | INLTELLIEV | TGNVVCKVSV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GSGDKVDSYK | ILILEIMEML | GYSRSIEDFF | PMFGWVDWLT | GLRGKVAKAA | KGVDDFLEGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LKEHLTARAS | NNASADNDFV | SILLEIQEAD | AGSTMDNECI | KSLIWDMLGA | GTETISTALE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WTLAALIKNP | DAMLKLQNEV | REIGKGKSKI | SEADLGKMTY | LQAVMKESMR | LYFTAPLLVP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RESRQDVKFM | GYDISAGTQV | LINVWAIARD | PSLWEKPEEF | RPERFLNSHI | DYKGFNYEYL |
| 430 | 440 | 450 | 460 | 470 | |
| PFGAGRRGCP | GIQFAMAVNE | LVVANVIHKF | NFELPDGERL | EDLDMTAVSG | ITLRKK |