C0MA42
Gene name |
aroA |
Protein name |
3-phosphoshikimate 1-carboxyvinyltransferase |
Names |
5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS |
Species |
Streptococcus equi subsp equi (strain 4047) |
KEGG Pathway |
seu:SEQ_0726 |
EC number |
2.5.1.19: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for C0MA42
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-C0MA42-F1 | Predicted | AlphaFoldDB |
No variants for C0MA42
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for C0MA42 | |||||
No associated diseases with C0MA42
3 regional properties for C0MA42
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Enolpyruvate transferase domain | 5 - 421 | IPR001986 |
| conserved_site | 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site | 86 - 100 | IPR023193-1 |
| conserved_site | 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site | 337 - 355 | IPR023193-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.19 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-phosphoshikimate 1-carboxyvinyltransferase activity | Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| aromatic amino acid family biosynthetic process | The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). |
| cellular amino acid biosynthetic process | The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. |
| chorismate biosynthetic process | The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKLKTKAKAL | RGRLRVPGDK | SISHRAVIFG | AIAEGQTVIH | GLLRGQDVLA | TIQAFRDLGV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TIYESADSLI | IEGRGFKGLK | PAQKPLDMGN | SGTSMRLLAG | LLAAQDFSVQ | LLGDDSLSRR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PMDRITIPLS | LMGAELSGQG | EKELPPLIVK | GCQELRPIHY | QLPVASAQVK | SAILLAALQT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QGETVILEKE | LTRNHTEEMI | EQFGGKLSVA | GKQISIKGPQ | RLQGQTLQIP | GDLSSAAFWL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAGLIVPGSD | LVLENVGINP | TRTGLLEVIE | KMGGRISYQA | VDKDRQAATL | KVSYSTLKGI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EISGDLIPRL | IDELPVIALL | ATQAQGTTYI | RDAQELRVKE | TDRIQAVTDV | LGQMGADIQA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TEDGMVTRGK | TPLHGAAVST | CGDHRIGMMT | AIAALLVEEG | QVTLERAEAI | LTSYPDFFKD |
| LERLWHD |