B9XZG7

PR
Gene name
rnaJ (HPB128_16g80)
Protein name
Ribonuclease J
Names
Species
Helicobacter pylori (strain B128)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-162 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for B9XZG7

Entry ID Method Resolution Chain Position Source
8CGL EM 410 A A/B/C/D 2-691 PDB
AF-B9XZG7-F1 Predicted AlphaFoldDB

No variants for B9XZG7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9XZG7

No associated diseases with B9XZG7

4 regional properties for B9XZG7

Type Name Position InterPro Accession
domain Metallo-beta-lactamase 152 - 351 IPR001279
conserved_site Ribonuclease J, conserved site 500 - 528 IPR001587
domain Zn-dependent metallo-hydrolase, RNA specificity domain 491 - 539 IPR011108
domain Ribonuclease J, C-terminal 590 - 685 IPR041636

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • The RNaseJ-RhpA complex co-localizes with 70S ribosomes and polysomes; remains associated with ribosomes in the absence of RhpA
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
5'-3' exoribonuclease activity Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
RNA binding Binding to an RNA molecule or a portion thereof.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDNNHYENN ESNENSSENS KVDEARAGAF ERFTNRKKRF RENAQKNGES SHHEAPSHHK
70 80 90 100 110 120
KEHRPNKKPN NHHKQKHAKT RNYAKEELDS NKVEGVTEIL HVNERGTLGF HKELKKGVET
130 140 150 160 170 180
NNKIQVEHLN PHYKMNLNSK ASVKITPLGG LGEIGGNMMV IETPKSAIVI DAGMSFPKEG
190 200 210 220 230 240
LFGVDILIPD FSYLHQIKDK IAGIIITHAH EDHIGATPYL FKELQFPLYG TPLSLGLIGS
250 260 270 280 290 300
KFDEHGLKKY RSYFKIVEKR CPISVGEFII EWIHITHSII DSSALAIQTK AGTIIHTGDF
310 320 330 340 350 360
KIDHTPVDNL PTDLYRLAHY GEKGVMLLLS DSTNSHKSGT TPSESTIAPA FDTLFKEAQG
370 380 390 400 410 420
RVIMSTFSSN IHRVYQAIQY GIKYNRKIAV IGRSMEKNLD IARELGYIHL PYQSFIEANE
430 440 450 460 470 480
VAKYPDNEVL IVTTGSQGET MSALYRMATD EHRHISIKPN DLVIISAKAI PGNEASVSAV
490 500 510 520 530 540
LNFLIKKEAK VAYQEFDNIH VSGHAAQEEQ KLMLRLIKPK FFLPVHGEYN HVARHKQTAI
550 560 570 580 590 600
SCGVPEKNIY LMEDGDQVEV GPAFIKKVGT IKSGKSYVDN QSNLSIDTSI VQQREEVASA
610 620 630 640 650 660
GVFAATIFVN KNKQALLESS QFSSLGLVGF KDEKHLIKEI QGGLEMLLKS SNAEILNNPK
670 680 690
KLEDHTRNFI RKALFKKFRK YPAIICHAHS F