B9LL91

PR
Gene name
rpoB
Protein name
DNA-directed RNA polymerase subunit beta
Names
RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta
Species
Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)
KEGG Pathway
chl:Chy400_0949
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9LL91

Entry ID Method Resolution Chain Position Source
AF-B9LL91-F1 Predicted AlphaFoldDB

No variants for B9LL91

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9LL91

No associated diseases with B9LL91

8 regional properties for B9LL91

Type Name Position InterPro Accession
domain DNA-directed RNA polymerase, subunit 2, hybrid-binding domain 732 - 1118 IPR007120
conserved_site RNA polymerase, beta subunit, conserved site 971 - 983 IPR007121
domain RNA polymerase Rpb2, domain 7 1120 - 1194 IPR007641
domain RNA polymerase Rpb2, domain 2 158 - 219 IPR007642-1
domain RNA polymerase Rpb2, domain 2 263 - 378 IPR007642-2
domain RNA polymerase, beta subunit, protrusion 46 - 422 IPR007644
domain RNA polymerase Rpb2, domain 3 437 - 505 IPR007645
domain DNA-directed RNA polymerase, beta subunit, external 1 domain 612 - 671 IPR019462

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
ribonucleoside binding Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPPLIESVVL QPLIAPIDPG ADGRRSRRIE RRSFARIKDA IDLPLLIETQ LKSFEWFKRE
70 80 90 100 110 120
GLRELFDEIS PITDFTGKNL ELHFRDYTFG EPRYDEFECR ERDLTYAAPL RVRVELRILT
130 140 150 160 170 180
TGEIKESEIF LGDFPIMTDN GTFVYNGAER VVVSQLIRSP GVYFKDEKEP TSGRSLHTAK
190 200 210 220 230 240
LIPNRGAWLE FETNKRDVIS VKVDRKRKIP VTILLRAITA WIAEENGNGR WVPDNELDKF
250 260 270 280 290 300
GHNDQIIELF RHVDTVPEHP YIHATLDKDP SRNAKEALLE LYKRLRPGDP PTLENARSLI
310 320 330 340 350 360
ESLLFSPRRY DLAKVGRYKL NKNLWERDVR RDGAKAPDLS VRVLLPRDIF RIVEQLILLN
370 380 390 400 410 420
NGHGRPDDID HLGNRRVRTV GELIQQQFRV GLLRLERVVK ERMSLQDPAS ATPNGLINIR
430 440 450 460 470 480
PVVAAMREFF GGSQLSQFMD QTNPLAELTN KRRLSALGPG GLSRDRAGFE VRDVHHSHYG
490 500 510 520 530 540
RICPVETPEG PNIGLIGTMS TFARVNEMGF LETPYRKVYN SVDNVQVWKE KGILLRDVRD
550 560 570 580 590 600
LRTGDLIAAK GTRVNDEIAR QITIGLLRGQ ILREDIVDPD TDELIAEAGT EINRALAERI
610 620 630 640 650 660
VELPIKHIKI RPVVSQEVDY LSADEEDRFV IVQANAPLDQ HNRFLDTIVS CRFGEDFVSE
670 680 690 700 710 720
RVERVDYMDV SPKQVVSVST SLIPFLEHDD ANRALMGSNM QRQAVPLLRP DAPIVGTGME
730 740 750 760 770 780
YRAARDSGQV IVARRDGVVV STTSERIVIE EDDGNQTEYR LRKFMRSNQD TCINQRPAVV
790 800 810 820 830 840
RGQRVKAGDV IADSSSTDQG ELALGQNVLV AYMPWEGGNF EDAILVSERL VREDIFTSIH
850 860 870 880 890 900
IEKYEVEARD TKLGPEEITR DIPNVGQESL RNLDERGIIY IGAEVQPNDI LVGKITPKGE
910 920 930 940 950 960
TDLTAEERLL RAIFGEKARE VKDSSLRVPN GVRGKVIDVK VFSRSEGAEL PVGVNQTVRV
970 980 990 1000 1010 1020
LLCQKRKISA GDKMAGRHGN KGVVSRVLPI EDMPFLPDGR PVDIILNPIG VPSRMNIGQI
1030 1040 1050 1060 1070 1080
LETHLGWAAA RLGFRVATPV FDGAHEDQIK DLLVQAGLPA DGKVTLYDGR TGERFDNPVT
1090 1100 1110 1120 1130 1140
VGYAYMLKLA HLVEDKIHAR STGPYSLVTQ QPLGGKAQFG GQRFGEMEVW ALEAYGAAYT
1150 1160 1170 1180 1190 1200
LQEMLTVKSD DVVGRVKTYE AIVKGEPIQE AGVPESFKVL IKELQSLGLS VEVLSADEKP
1210 1220
VELSDDLDSD IGALEGINLS GMERGEF