B9KYR9

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2)
KEGG Pathway
tro:trd_0623
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

689-790 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9KYR9

Entry ID Method Resolution Chain Position Source
AF-B9KYR9-F1 Predicted AlphaFoldDB

No variants for B9KYR9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9KYR9

No associated diseases with B9KYR9

9 regional properties for B9KYR9

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 15 - 145 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 333 - 466 IPR001247-2
domain S1 domain 631 - 702 IPR003029
domain K Homology domain 564 - 629 IPR004087
domain K Homology domain, type 1 568 - 625 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 148 - 208 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 470 - 540 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 242 - 330 IPR015848
domain RNA-binding domain, S1 632 - 702 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPPIIHERSI EIAGRLLTIE TGRVAEQADG AVLVRYGETV VLTTVVGAKQ PVEGIDFFPL
70 80 90 100 110 120
TVEYEEKMYA AGKIPGGFFR REGKPSEAAI LAARLTDRPI RPLFPKGYRN EVQVISTVLS
130 140 150 160 170 180
ADQENEPDVL SIIGASAALT LSDIPWYGPV GAVRIGELDG ELVINPTSHQ LLESRMDIVV
190 200 210 220 230 240
AGTADAILMV EGQANEISED RFIEAVVRAH QEIKRIVAVQ LELQAVAGKP KREFVPPQEN
250 260 270 280 290 300
VELKQQIADY LGDRLREAVF NPDKTLRVQA TAALREEVIA HFVPNEPLAI GTPQSGLPTA
310 320 330 340 350 360
KEVGDLFDSL VKELVRRTIL EQGERPDGRK PDEIREIWIQ VGLLPRPHGS ALFTRGQTQV
370 380 390 400 410 420
LTVCTLGTKE EEQFLDSLGI EETKRYMHHY NFPPFSTGEI RRLRGPSRRD IGHGALAERA
430 440 450 460 470 480
LLAVLPSEDE FPYTMRLVSE VLSSNGSTSM ASVCGSSLAL MDAGVPIRKP VAGVAMGLVT
490 500 510 520 530 540
DQTTGRYTIL TDIQGIEDAL GDMDFKVAGT RDGITAIQMD IKVMGITPEI MRDALEQARR
550 560 570 580 590 600
GRLFILDKMS EVIDAPRPEM SPYAPRILRI KIKPEQIGEV IGPGGRVIRA IQEQTGTKIS
610 620 630 640 650 660
IEEDGTVFIS AANEDAARRA VREIERLTRV PEVGEIFYGR VVTIIPSGAF VEILPGKDGF
670 680 690 700 710 720
LHISEIAPER VRSVEDVLKV GQEINVMVIG VRPDGKINLS RKALLEKEAA ERAATAQAPA
730 740 750 760 770 780
DGRSHQPRAP QRPSGTAQPE RRPGPPTPRR PEQRGPSRPP RPQAQRSTPP PGQYRIGDRL
KELLGEDEPN