B9KIE3
Gene name |
pnp |
Protein name |
Polyribonucleotide nucleotidyltransferase |
Names |
Polynucleotide phosphorylase, PNPase |
Species |
Anaplasma marginale (strain Florida) |
KEGG Pathway |
amf:AMF_391 |
EC number |
2.7.7.8: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B9KIE3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B9KIE3-F1 | Predicted | AlphaFoldDB |
No variants for B9KIE3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B9KIE3 | |||||
No associated diseases with B9KIE3
7 regional properties for B9KIE3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exoribonuclease, phosphorolytic domain 1 | 14 - 143 | IPR001247-1 |
| domain | Exoribonuclease, phosphorolytic domain 1 | 328 - 461 | IPR001247-2 |
| domain | S1 domain | 623 - 694 | IPR003029 |
| domain | K Homology domain | 557 - 622 | IPR004087 |
| domain | K Homology domain, type 1 | 562 - 618 | IPR004088 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 147 - 211 | IPR015847 |
| domain | RNA-binding domain, S1 | 625 - 694 | IPR022967 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.8 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| polyribonucleotide nucleotidyltransferase activity | Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFDITRKCVE | WGDRLLVIES | GKIARQADGA | VVVDYGGTSV | LSTVVSQKSK | EPVDFLPLTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QFLAKSYAIG | RIPGGFFKRE | GKPSDRETLI | SRLVDRSIRP | LFPTGFCDEI | VIVCNLLSYD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QVSPPETVAL | IGAAAALAIS | GIPFPTPIAG | AKIGYIREEE | RYILNPSAEE | LARSELDMFY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SGTKSSVVMV | ESEASELSEE | EMLGAVTFGH | ENCAQVLDLI | EEFAEAAGPK | DVVEFVPHDI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GKVVSDISSG | YSEKFSVAYS | DHNKKPECSS | LMPPGKACTQ | ICAGKHVEES | GEYTEQEVLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AIKTFERSLV | RARVLDTLKR | VDGRGFDQIR | NIEIEVDLIP | RSHGSALFTR | GDTQALVITA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGTPQDEQVV | DGFDGDRRER | FLLHYNFPSY | AVGEAAALRP | PGRREIGHGK | LAWRAIHPVL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PTKADFPYTI | RVVSEITESD | GSSSMATVCG | ASLALMDTGV | PLKSSVAGIA | MGLIKEGDRY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AVLSDIIGDE | DYLGDMDFKV | AGTKDGITAL | QMDMKIRGIG | FDIIEKSLQQ | AKDGRLFIIG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KMDKVIKESR | EGVRDHVPRM | ESMIIDKNKI | KNVIGTGGKN | VREICEKTGV | KIEISQDGTV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| MIYAVSRDAV | EEAKNMIMCI | VSEPEVGKVF | SGVISEIAKY | GAFVSFLGGR | RGLVHISEIK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NEHIGSVSDV | LAVDDKVKVL | VIGIDKDHVQ | LSMRRVDQDS | GDLLEHESYS | SNKKNGPQFG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| DASGGASGFR | DYASGPARER | RRSGGSGGRP | VRRRSAGSSG | SGSGGCYSVP | QHVGTPDPVH |
| 790 | 800 | ||||
| GNDRRRGSGP | QHASGGGGNK | KPRFF |