B9KD35
Gene name |
dapE |
Protein name |
Succinyl-diaminopimelate desuccinylase |
Names |
SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase |
Species |
Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) |
KEGG Pathway |
cla:CLA_1152 |
EC number |
3.5.1.18: In linear amides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B9KD35
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B9KD35-F1 | Predicted | AlphaFoldDB |
No variants for B9KD35
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B9KD35 | |||||
No associated diseases with B9KD35
3 regional properties for B9KD35
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ArgE/DapE/ACY1/CPG2/YscS, conserved site | 60 - 69 | IPR001261-1 |
| conserved_site | ArgE/DapE/ACY1/CPG2/YscS, conserved site | 94 - 129 | IPR001261-2 |
| domain | Peptidase M20, dimerisation domain | 168 - 269 | IPR011650 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.1.18 | In linear amides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| cobalt ion binding | Binding to a cobalt ion (Co). |
| succinyl-diaminopimelate desuccinylase activity | Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| diaminopimelate biosynthetic process | The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. |
| lysine biosynthetic process via diaminopimelate | The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQVVEIFKEL | CKFKSITPDD | DGALNYIAVE | LSEFEAFFIE | KEGVKNLLLT | KKFSDDGEHL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AFGGHVDVVP | AGEGWSNDPF | EPLDKDGFIY | ARGAQDMKSG | VAAFMCAVKE | VENFKGRISL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILTSDEEGEA | KFGTLEVLKF | MKEKDILPDF | AVVAEPTCDK | KFGDSIKVGR | RGSINAKLLI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KGKQGHVAYP | QKCINPVHNF | ASALKFLAGF | DLDPGDEAFA | PSKIVITDIR | GGMEVCNVTP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NDLKLMFNVR | NSPQTSLEDV | KAYVEKTCEG | LDYELSINQS | SKPFLTQSDS | KIVQKLNESV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QKITQVVPEL | NTKGGTSDAR | YFAEFGVKVV | EFGVCNDRIH | AIDERVSIEE | LEKLYLVFKD |
| LLENFN |