B9K884
Gene name |
tuf |
Protein name |
Elongation factor Tu |
Names |
EF-Tu |
Species |
Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E) |
KEGG Pathway |
tna:CTN_0991 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for B9K884
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5W75 | X-ray | 230 A | A/B/C/D | 9-400 | PDB |
| AF-B9K884-F1 | Predicted | AlphaFoldDB |
No variants for B9K884
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B9K884 | |||||
No associated diseases with B9K884
7 regional properties for B9K884
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 10 - 203 | IPR000795 |
| domain | Translation elongation factor EFTu/EF1A, C-terminal | 297 - 391 | IPR004160 |
| domain | Translation elongation factor EFTu-like, domain 2 | 224 - 292 | IPR004161 |
| domain | Small GTP-binding protein domain | 13 - 147 | IPR005225 |
| conserved_site | Tr-type G domain, conserved site | 51 - 66 | IPR031157 |
| domain | Elongation factor Tu, domain 2 | 210 - 296 | IPR033720 |
| domain | Elongation factor Tu (EF-Tu), GTP-binding domain | 11 - 202 | IPR041709 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| translation elongation factor activity | Functions in chain elongation during polypeptide synthesis at the ribosome. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKEKFVRTK | PHVNVGTIGH | IDHGKSTLTA | AITKYLSLKG | LAQYVPYDQI | DKAPEEKARG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ITINITHVEY | ETEKRHYAHI | DCPGHADYIK | NMITGAAQMD | GAILVVAATD | GPMPQTREHV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLARQVEVPY | MIVFINKTDM | VDDPELIELV | EMEVRDLLSQ | YEYPGDEVPV | IKGSALKALE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| APDDPNHEAY | KPIQELLDAM | DNYIPDPQRD | VDKPFLMPIE | DVFSITGRGT | VVTGRIERGR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IRPGDEVEII | GLSYEIRKTV | VTSVEMFRKE | LDEGIAGDNV | GCLLRGIDKD | EVERGQVLAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PGSIKPHKRF | KAEVYVLKKE | EGGRHTPFTK | GYKPQFYIRT | ADVTGEIVGL | PEGVEMVMPG |
| 370 | 380 | 390 | |||
| DHVEMEIELI | YPVAIEKGQR | FAIREGGRTV | GAGVVTEVIE |