B9K867

PR
Gene name
dapH
Protein name
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
Names
Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase
Species
Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E)
KEGG Pathway
tna:CTN_0974
EC number
2.3.1.89: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9K867

Entry ID Method Resolution Chain Position Source
AF-B9K867-F1 Predicted AlphaFoldDB

No variants for B9K867

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9K867

No associated diseases with B9K867

4 regional properties for B9K867

Type Name Position InterPro Accession
repeat Hexapeptide repeat 122 - 157 IPR001451-1
repeat Hexapeptide repeat 166 - 201 IPR001451-2
domain 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal 7 - 88 IPR013710
conserved_site Hexapeptide transferase, conserved site 175 - 203 IPR018357

Functions

Description
EC Number 2.3.1.89 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
tetrahydrodipicolinate N-acetyltransferase activity Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVNEVDARE IIEMIAKSKK KTPIVAYIKG KLDGIDFSKF KFFGNDQFGV LFGEYEDFRE
70 80 90 100 110 120
LLEKYGEKIE DYHLEVKARN SALPLADITK YRARIEPGAI IRDMVEIGEG AVIMMGAVIN
130 140 150 160 170 180
VGAVIGEGTM IDMNAVVGGR AIIGKKCHIG AGAVIAGVIE PPSAKPVVIE DEVVVGANAV
190 200 210 220 230
ILEGVTVGKG SVVAAGAVVT KDVPPYTVVA GVPARVIKQI DEKTKEKTRI VDELRNLE