B9JSD8
Gene name |
lpxK |
Protein name |
Tetraacyldisaccharide 4'-kinase |
Names |
Lipid A 4'-kinase |
Species |
Agrobacterium vitis (strain S4 / ATCC BAA-846) (Rhizobium vitis (strain S4)) |
KEGG Pathway |
avi:Avi_0897 |
EC number |
2.7.1.130: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B9JSD8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B9JSD8-F1 | Predicted | AlphaFoldDB |
No variants for B9JSD8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B9JSD8 | |||||
No associated diseases with B9JSD8
No regional properties for B9JSD8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B9JSD8 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.130 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| tetraacyldisaccharide 4'-kinase activity | Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKLHAPSFWW | QKASFPALAL | WPLSFLYGRI | AARRMRGSSA | YAPAVPVICI | GNVTLGGAGK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TPTALALAKA | ALAMGLKPGF | LSRGYGGTVR | RPTLVDPGHH | TAKDVGDEPL | LLASVAPTVV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ASRRRDGARE | LERQGIDLII | MDDGFQSAQI | RIDCAVVVTD | SYKGDGNGFV | FPAGPLRAPL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AIQFQKLDML | LVVGKGDAAI | PMVRRGARMG | KPVLTAQLHP | LPGPNLRGQR | VLAYAGIADP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EKFYRTLREL | GADIVVARGF | GDHQPLSAAA | IAELIEEAEA | KNLSLVTTAK | DQARLRGSRR |
| 310 | 320 | 330 | 340 | ||
| GGAGQDRAQE | LLAKSTVIEI | EMIFDDPAVP | ARVIDQAQDR | FRRSR |