B9IZI6

PR
Gene name
rpoB
Protein name
DNA-directed RNA polymerase subunit beta
Names
RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta
Species
Bacillus cereus (strain Q1)
KEGG Pathway
bcq:BCQ_0115
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

769-841 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9IZI6

Entry ID Method Resolution Chain Position Source
AF-B9IZI6-F1 Predicted AlphaFoldDB

No variants for B9IZI6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9IZI6

No associated diseases with B9IZI6

3 regional properties for B9IZI6

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit, C-terminal 251 - 312 IPR011260
domain DNA-directed RNA polymerase, insert domain 57 - 156 IPR011262
domain DNA-directed RNA polymerase, RpoA/D/Rpb3-type 21 - 231 IPR011263

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
ribonucleoside binding Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTGQLVQYGR HRQRRSYARI SEVLELPNLI EIQTSSYQWF LDEGLREMFQ DISPIEDFTG
70 80 90 100 110 120
NLSLEFIDYS LGEPKYSVDE CKERDVTYAA PLRVKVRLIN KETGEVKEQD VFMGDFPLMT
130 140 150 160 170 180
ETGTFVINGA ERVIVSQLVR SPSVYYSGKV DKNGKRGFTA TVIPNRGAWL EYETDAKDVV
190 200 210 220 230 240
YVRIDRTRKL PVTVLLRALG FGSDQEITEL LGDNEYLSNT LEKDNTDSTE KALLEIYERL
250 260 270 280 290 300
RPGEPPTVEN AKSLLVSRFF DPKRYDLANV GRYKINKKLH IKNRLFNQRL AETLVDPETG
310 320 330 340 350 360
EILAAEGTIL DRRTLDRILP YLEKNIGFKT AKPMGGVVEG DVELQSIKIY APESEGERVI
370 380 390 400 410 420
NVIGNANITR DVKHITPGDI LASISYFFNL LYKVGDTDDI DHLGNRRLRS VGELLQNQFR
430 440 450 460 470 480
IGLSRMERVV RERMSIQDTN AITPQALINI RPVIASIKEF FGSSQLSQFM DQTNPLAELT
490 500 510 520 530 540
HKRRLSALGP GGLTRERAGF EVRDVHYSHY GRMCPIETPE GPNIGLINSL SSFAKVNEFG
550 560 570 580 590 600
FIETPYRRVD PETGLVTGHV DYLTADEEDN YVVAQANMKL SEEGEFLDED IVARFRGENI
610 620 630 640 650 660
VTNKERIDYM DVSPKQVVSA ATACIPFLEN DDSNRALMGA NMQRQAVPLM NPESPIVGTG
670 680 690 700 710 720
MEYVSAKDSG AAVICKHPGI VERVEAREVW VRRYVEVDGQ TVKGDLDRYK MQKFIRSNQG
730 740 750 760 770 780
TCYNQRPIVS VGNEVVKGEI LADGPSMELG ELALGRNVLV GFMTWDGYNY EDAIIMSERL
790 800 810 820 830 840
VKDDVYTSIH IEEYESEARD TKLGPEEITR DIPNVGEDAL RNLDERGIIR VGAEVKDGDL
850 860 870 880 890 900
LVGKVTPKGV TELTAEERLL HAIFGEKARE VRDTSLRVPH GGGGIILDVK VFNREDGDEL
910 920 930 940 950 960
PPGVNQLVRA YIVQKRKISE GDKMAGRHGN KGVISRILPE EDMPYLPDGT PIDIMLNPLG
970 980 990 1000 1010 1020
VPSRMNIGQV LELHLGMAAR YLGIHIATPV FDGAREEDVW GTIEEAGMAN DAKTILYDGR
1030 1040 1050 1060 1070 1080
TGEPFDNRVS VGVMYMIKLA HMVDDKLHAR STGPYSLVTQ QPLGGKAQFG GQRFGEMEVW
1090 1100 1110 1120 1130 1140
ALEAYGAAYT LQEILTVKSD DVVGRVKTYE AIVKGENVPE PGVPESFKVL IKELQSLGMD
1150 1160 1170
VKMMSSDDTE IEMRDTEDDD DHQSADKLNV EVETTKE