B9EBE9

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Macrococcus caseolyticus (strain JCSC5402)
KEGG Pathway
mcl:MCCL_0853
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-178 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9EBE9

Entry ID Method Resolution Chain Position Source
AF-B9EBE9-F1 Predicted AlphaFoldDB

No variants for B9EBE9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9EBE9

No associated diseases with B9EBE9

6 regional properties for B9EBE9

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 227 - 396 IPR000795
domain Small GTP-binding protein domain 229 - 387 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 149 - 199 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 503 - 617 IPR023115
domain Translation initiation factor IF-2, domain II 403 - 497 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKRIYEYA KEVSLKSKDI IDALKKMNIE ASSHMQVIEA KEIAALDKIF KKSDTKSEVK
70 80 90 100 110 120
SEQKAEAKKE EPNKEQPKKE EPKKQSDQKR PQNNNQKRNP NHRPGSHNKP GTGGPSKNKK
130 140 150 160 170 180
GKGKGKQKPE PKQEVPVVKE TPSKITYEEG ITVGELAEKL GKDASEIVKN LFMVGIMANI
190 200 210 220 230 240
NQSLNQEAIE LICDEYGVEA ELEVVVDATD LETYFEDVDA NEEDIMERPP VVTIMGHVDH
250 260 270 280 290 300
GKTTLLDSIR NTRVTAGEAG GITQHIGAYQ IEYNDKPITF LDTPGHAAFT TMRARGAQVT
310 320 330 340 350 360
DITILVVAAD DGVMPQTVEA INHAKAAEVP IIVAVNKIDK PTANPDRVMQ ELGEHGLYPE
370 380 390 400 410 420
DWGGDTIFVQ LSAIKGDGID DLLEMIQLVT EVEELKANPK RTAIGTVIEA ELDKSRGPAA
430 440 450 460 470 480
SLLVQDGTLE IGDSIVVGNT FGRVRAMVND LGKRIKTAGP SLPVEITGLQ DVPLAGDRFV
490 500 510 520 530 540
VFKDEKKARR IGEARQQQNI LAQRQESQKV SLDNLFEQMK QGEMKDLNVI IKGDVQGSVE
550 560 570 580 590 600
ALAASLMKID VEGVNVRIIH TAVGAINESD VTLASASNGI IIGFNVRPDV NAKRAAEAEG
610 620 630 640 650 660
VDMRLHRIIY KVIEEIESAM KGMLDPEFEE KVIGQAEVRQ TINISKVGTV AGSYVTDGKI
670 680 690 700 710 720
TRDSQVRIIR DGIVVYEGQV DALKRFKDDV REVAQGYECG ITIENFNDIK EGDIFEAFVM
EEIKRA