B9DPB9

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Staphylococcus carnosus (strain TM300)
KEGG Pathway
sca:SCA_0945
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

756-869 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9DPB9

Entry ID Method Resolution Chain Position Source
AF-B9DPB9-F1 Predicted AlphaFoldDB

No variants for B9DPB9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9DPB9

No associated diseases with B9DPB9

5 regional properties for B9DPB9

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 623 - 812 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 13 - 124 IPR007695
domain DNA mismatch repair protein MutS, core 282 - 605 IPR007696
domain DNA mismatch repair protein MutS, connector domain 133 - 263 IPR007860
domain DNA mismatch repair protein MutS, clamp 442 - 532 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNVTPMMQQ YLKIKSQYQD CLLFFRLGDF YEMFFEDAKE ASRVLEITLT KRDAKKENPI
70 80 90 100 110 120
PMCGVPYHSA ESYIETLINE GYKVAICEQM EDPKTTKGMV KREVIRVVTP GTIMNQGGMD
130 140 150 160 170 180
EKQNNYILSF IKDGATIAVS YCDVSTGELK VTKFNDESML LNEITTINPN EIVAADQVSE
190 200 210 220 230 240
SLKQQMSLAT ETITVVDEIS NEAYEVNQVE DTLMHQAVQL LLDYIHHTQK RNMNHIEDAQ
250 260 270 280 290 300
VYEAIDYMKM DYYAKRNLEL TESIRLKSKK GTLLWLMDET KTPMGARRLK QWIDRPLIYK
310 320 330 340 350 360
QAINERLDAV SQLIDRFIER DTLRNYLNQV YDIERLVGRV SYGNVNARDL IQLKHSIAEI
370 380 390 400 410 420
PNIKALLDDF DDALPEQFRQ LEPLNDLLDL LEKSLVEEPP ISVKDGGLFK QGFNQQLDEY
430 440 450 460 470 480
LEASVNGKQW LAQLQAKERE RTGIKSLKIS FNKVFGYFIE ITRANLKGFE PADFGYNRKQ
490 500 510 520 530 540
TLSNAERFIT DELKEKEDII LGAEDKAVEL EYQLFAQLRE EVKAYTERLQ KQAKLISEID
550 560 570 580 590 600
CLQSFAEIAQ KYNYVRPEFS DDKTLDLVDS RHPVVERVMD YNDYVPNDCR LDDDQFIYLI
610 620 630 640 650 660
TGPNMSGKST YMRQVAIISI MAQMGAYVPC GSAVLPIFDQ IFTRIGAADD LVSGKSTFMV
670 680 690 700 710 720
EMLEAQKALT YATEDSLIIF DEIGRGTSTF DGLALAQAMI EYVAETSHAK TLFSTHYHEL
730 740 750 760 770 780
TTLDQSLECL KNVHVAANEY QGELIFLHKV KDGAVDDSYG IQVAKLADLP DRVIERAQVI
790 800 810 820 830 840
LDAFEEKDKP QPQISHLQQT ESFVREPEIE DIQDKKEPET EQFQQGAFDL FETPPVESEI
850 860
EAELKKINIS NMTPLQALNK LSELQNQLK