B9DMJ0

PR
Gene name
acpS
Protein name
Holo-[acyl-carrier-protein] synthase
Names
Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS
Species
Staphylococcus carnosus (strain TM300)
KEGG Pathway
sca:SCA_1577
EC number
2.7.8.7: Transferases for other substituted phosphate groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B9DMJ0

Entry ID Method Resolution Chain Position Source
AF-B9DMJ0-F1 Predicted AlphaFoldDB

No variants for B9DMJ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B9DMJ0

No associated diseases with B9DMJ0

2 regional properties for B9DMJ0

Type Name Position InterPro Accession
domain Phosphopantetheine-protein transferase domain 1 - 116 IPR004568
domain 4'-phosphopantetheinyl transferase domain 4 - 108 IPR008278

Functions

Description
EC Number 2.7.8.7 Transferases for other substituted phosphate groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
holo-[acyl-carrier-protein] synthase activity Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIYGIGIDLI EIGRIKTLME RQKKLPERIL SKDELTKFES FSHEQRRAEF LAGRFACKEA
70 80 90 100 110
FSKALGTGLG KHVSFQDINC QNDELGRPYI RYEGFKVHVS ITHTENYAAS QVILEKM