B8ZU74
Gene name |
fgd |
Protein name |
F420-dependent glucose-6-phosphate dehydrogenase |
Names |
FGD, G6PD |
Species |
Mycobacterium leprae (strain Br4923) |
KEGG Pathway |
mlb:MLBr00269 |
EC number |
1.1.98.2: With other, known, acceptors |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B8ZU74
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B8ZU74-F1 | Predicted | AlphaFoldDB |
No variants for B8ZU74
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B8ZU74 | |||||
No associated diseases with B8ZU74
1 regional properties for B8ZU74
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Luciferase-like domain | 10 - 307 | IPR011251 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.98.2 | With other, known, acceptors |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| coenzyme F420 binding | Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| glucose-6-phosphate dehydrogenase (coenzyme F420) activity | Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420. |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAELRLGYKA | SAEQFAPREL | VELGVAAEAH | GMDSATVSDH | FQPWRHQGGH | ASFSLSWMTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VGERTNRILL | GTSVLTPTFR | YNPAVIGQAF | ATMGCLYPNR | VFLGVGTGEA | LNEVATGYQG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AWPEFKERFA | RLRESVRLMR | ELWRGDRVDF | DGDYYQLKGA | SIYDVPEGGV | PIYIAAGGPE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VAKYAGRAGE | GFVCTSGKGE | ELYTEKLIPA | VLEGAAVAGR | DADDIDKMIE | IKMSYDPDPE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QALSNIRFWA | PLSLAAEQKH | SIDDPIEMEK | VADALPIEQV | AKRWIVVSDP | DEAVARVGQY |
| 310 | 320 | 330 | |||
| VTWGLNHLVF | HAPGHNQRRF | LELFEKDLAP | RLRRLG |