B8ZRK7

PR
Gene name
argR
Protein name
Arginine repressor
Names
Species
Mycobacterium leprae (strain Br4923)
KEGG Pathway
mlb:MLBr01411
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8ZRK7

Entry ID Method Resolution Chain Position Source
AF-B8ZRK7-F1 Predicted AlphaFoldDB

No variants for B8ZRK7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8ZRK7

No associated diseases with B8ZRK7

2 regional properties for B8ZRK7

Type Name Position InterPro Accession
domain Arginine repressor, C-terminal 97 - 162 IPR020899
domain Arginine repressor, DNA-binding domain 13 - 81 IPR020900

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
arginine binding Binding to 2-amino-5-(carbamimidamido)pentanoic acid.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

2 GO annotations of biological process

Name Definition
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
protein complex oligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTHGASKTTP ETTRAGRQAR IVAILSSTSV RSQSELATLL ADDGIDVTQA TLSRDLEELG
70 80 90 100 110 120
AVKLRGADGG VGVYVVPEDG SPVRGVSGGT ARLSRLLSEL LVSADSSANL AVLRTPPGAA
130 140 150 160
DYLASAIDRA ALPYVVGTIA GDDTVFVAAR EPMTGSELAT VLESLNR