Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B8NJL4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B8NJL4-F1 | Predicted | AlphaFoldDB |
No variants for B8NJL4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B8NJL4 | |||||
No associated diseases with B8NJL4
Functions
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| endoplasmic reticulum inheritance | The partitioning of endoplasmic reticulum between daughter cells at cell division. |
| endoplasmic reticulum membrane fusion | The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATNGHFASI | GNSASDTTAY | EHGVQVIDEN | KEFNPNLSQY | LSLENVTPSG | FNYHLISVFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SQSTGKSTLL | NHLFGTHFSV | MSELERRQTT | KGIWMSKNKN | ESSSMASNIL | VMDVEGTDGR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ERGEDQDFER | KSALFALATS | EVLIVNIWEH | QVGLYQGANM | GLLKTVFEVN | LQLFLKDKNT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| THRSLLFFVI | RDYSGMTPLQ | NLQKTLMEDM | ARLWDSISKP | GGLENSNVHD | YFDFQFYGLP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HKGYQPEKFV | EETQKLSLRF | CDGQRDPNLD | ARKGEFSDGG | VFLPEYHRRI | PADGFSRYAE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GIWDQIVNNK | DLDLPTQQEL | LAQFRCDEIL | REVMVAFDET | IVPFEDKQSQ | AARLGEPEIL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GGLGAAMRSS | RTKAVKAFES | EASRYHKGVY | QRKRAELESK | ADTRLKTLFQ | GQLNAAHKSG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ISEFSEAVTA | AVKSGQKKGT | GYDFAEIVNE | EAKKAVDKFE | EVARATVVDG | TSWSDYKQEL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ALYEKELAEV | SARLRRDEMR | RLASRVERWV | QSRLGESVGL | EFNALGSGRA | GGGAPEKGDQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PTEKKFWDRV | WNVFVETVLD | AERRFTDRAS | SFDASLEEVD | VGLWRLRRKS | WGVLRAKIDE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| EMIEGNLLLK | LRENFEDKFR | YDDAGVPRIW | RPTDDIEGIY | TRARESTLTL | IPLLSKFRLD |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ETSAPPPLDR | WIGHTPSSAT | SADEEDLAPI | GGVDEEEGKS | LEEEMTIVSD | AKRQELTVRF |
| 730 | 740 | 750 | 760 | 770 | 780 |
| KKAADGVYVE | AKRSAIGGMT | QVPLYFYGLL | LALGWNEIIA | VLRNPAYFFL | LFVCAVGAYI |
| 790 | 800 | 810 | 820 | 830 | 840 |
| TYQLNLWGPI | IKMTEAASNQ | AVTEGKKRLR | EFLESSDTGR | QAIAMSTPGG | SGRGGEEHEM |
| 850 | |||||
| SRLNQQGKSA | AADEDVDDL |