B8JAX1

PR
Gene name
gpsA
Protein name
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
Names
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
Species
Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)
KEGG Pathway
acp:A2cp1_0425
EC number
1.1.1.94: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

224-313 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8JAX1

Entry ID Method Resolution Chain Position Source
AF-B8JAX1-F1 Predicted AlphaFoldDB

No variants for B8JAX1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8JAX1

No associated diseases with B8JAX1

5 regional properties for B8JAX1

Type Name Position InterPro Accession
conserved_site MnmG-related, conserved site 257 - 271 IPR020595-1
conserved_site MnmG-related, conserved site 352 - 375 IPR020595-2
domain tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal 385 - 597 IPR026904
domain MnmG, N-terminal domain 1 - 382 IPR040131
domain tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain 528 - 599 IPR047001

Functions

Description
EC Number 1.1.1.94 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glycerol-3-phosphate dehydrogenase complex An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate dehydrogenase [NAD+] activity Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

5 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
glycerol-3-phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerol-3-phosphate catabolic process The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
glycerophospholipid metabolic process The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRATVLGAGS WGTALASLLA GKGYTVTSWD KDAAVLDDIA RNHRNERYLP GLQLPPTLHA
70 80 90 100 110 120
SGEVAKALEG AELVVLAVPS HAVRPVVIEA KRHVHAGTPI VCVAKGIELD TLMTMTEVIE
130 140 150 160 170 180
DVLPVPLHPY LAVLSGPSFA KEVAKGLPTA VTVAARWERI AKQVQDAFHT KTFRPYTSGD
190 200 210 220 230 240
VVGCEIGGCV KNVVAIAAGI SDGMGFGANA MAALVTRGLA EITRLAVRKG ANPLTLSGLA
250 260 270 280 290 300
GLGDLVLTCS SDLSRNRTVG RGLAAGKTAD AIQRELGQVA EGVRNARSAR ELAKRLGVEM
310 320 330
PITEAIYRVL YEGLAPREAV TALMMRETKP EL