Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B8J7G5

Entry ID Method Resolution Chain Position Source
AF-B8J7G5-F1 Predicted AlphaFoldDB

No variants for B8J7G5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8J7G5

No associated diseases with B8J7G5

11 regional properties for B8J7G5

Type Name Position InterPro Accession
domain FERM domain 118 - 399 IPR000299
domain SAB domain 558 - 604 IPR007477
domain Band 4.1, C-terminal 815 - 921 IPR008379
domain FERM adjacent 405 - 451 IPR014847
domain FERM, N-terminal 122 - 184 IPR018979
domain FERM, C-terminal PH-like domain 313 - 403 IPR018980
conserved_site FERM conserved site 172 - 200 IPR019747-1
conserved_site FERM conserved site 279 - 308 IPR019747-2
domain FERM central domain 202 - 309 IPR019748
domain Band 4.1 domain 114 - 309 IPR019749
domain Band 4.1-like protein 3, FERM domain, F1 sub-domain 117 - 200 IPR030691

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • The tmRNA-SmpB complex associates with stalled 70S ribosomes
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
trans-translation A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKGKAGGKAA DAAEKVAASN RRARFDYDVE DTWEAGLVLT GSEVKSLREG NVNLSDAYAM
70 80 90 100 110 120
PRGEELWLLN CRIGEYQQAA HFGHAPLRDR KLLMNRAEID RVRGKVEQRG YTLVPLRIYF
130 140 150 160
KQGWAKVELG LARGRSHEDR RGAIAERESK REMDRALARG RRR