B8J1X9

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949 / MB)
KEGG Pathway
dds:Ddes_0054
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

685-743 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8J1X9

Entry ID Method Resolution Chain Position Source
AF-B8J1X9-F1 Predicted AlphaFoldDB

No variants for B8J1X9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8J1X9

No associated diseases with B8J1X9

8 regional properties for B8J1X9

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 18 - 148 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 333 - 464 IPR001247-2
domain S1 domain 629 - 704 IPR003029
domain K Homology domain 560 - 625 IPR004087
domain K Homology domain, type 1 565 - 621 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 151 - 212 IPR015847
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 250 - 329 IPR015848
domain RNA-binding domain, S1 628 - 697 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQDIFTPTR VTCQVGGKEI IIESGRMANQ AHGEVWIQCG GTVVLVTVCS QPLEFDKGFF
70 80 90 100 110 120
PLTVEYSEKM YAAGRIPGSF FRREIGRPSE RETLVARLID RPIRPLFPKG LNEDVQVLAS
130 140 150 160 170 180
VISADQENES DVLALTGASA ALMLSPLPFE GPVAGGRIAR VGGQFVLNPT FEQQAQSDLN
190 200 210 220 230 240
IVFAASGDAL TMVEGDARFI SEDVIIEALE WGRLQILPLV EIQHKLRELC GKPKMNFTPH
250 260 270 280 290 300
QDDEALVACV HELALANGME EALRVPEKMA RKDARKAVKD KVMETLKADP AWAENEAALK
310 320 330 340 350 360
AVSDILGGLE KKLVRARIVN EGTRIDGRDT TTVRPIQIQT GLLPRAHGSA LFRRGETKSL
370 380 390 400 410 420
VVATLGSSTD EQRMDSLTGD VTKRFMLHYN FPPFSVGEVK PVRVSRREIG HGALAEKSLR
430 440 450 460 470 480
PVLPADADFP FTLRVVAETM ESNGSSSMAA VCGGSLSLMD AGVPVSAPVA GVAMGLIKEG
490 500 510 520 530 540
EKFIVLTDIL GDEDALGDMD FKIAGTAEGV TGVQMDIKIT GLTTEIMRTA MQQAREGRLH
550 560 570 580 590 600
ILEEMAKAIA SPRKELSRYA PQHAEVFVNP DIIRLIIGPG GKNIKAITAA TGASVDIEDS
610 620 630 640 650 660
GRVSIFAPTA EALEKAREMV SYYDQRPDLG KNYNAKVRKI MEIGAIVEVL PNVEALVHVS
670 680 690 700 710 720
QLDVNRVEQP GDVARLGEDM LVKVIEINGD RIRASRKAVL LEEQGHPWNP EDTARPQRSD
730 740
RGDRGDRRGD RGGRDRRDRG DRR