B8GP02

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Thioalkalivibrio sulfidiphilus (strain HL-EbGR7)
KEGG Pathway
tgr:Tgr7_1003
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

7-299 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8GP02

Entry ID Method Resolution Chain Position Source
AF-B8GP02-F1 Predicted AlphaFoldDB

No variants for B8GP02

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8GP02

No associated diseases with B8GP02

8 regional properties for B8GP02

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 353 - 522 IPR000795
domain Translation elongation factor EFTu-like, domain 2 774 - 840 IPR004161
domain Small GTP-binding protein domain 356 - 512 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 276 - 326 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 64 - 101 IPR013575
domain Translation initiation factor IF- 2, domain 3 628 - 742 IPR023115
domain Translation initiation factor IF-2, domain II 528 - 622 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTVKQLS EVVGTPVERL IEQLGEAGVS VSDADQTVTE EQKLKLLEHL RKSHGKSSAA
70 80 90 100 110 120
GEGKKITLRR KSTTELRVTG SQGRAKTVSV EVRKRRTYVK RDEAEVAAPV EEAAPAPVLE
130 140 150 160 170 180
SKAAQIAKQV EEERKAAMDA SRRADEERKA AEAARKAEQE RKAAEEAARL EAEEAARREA
190 200 210 220 230 240
EEAARAAEPE TVAEAVEAAV APPPSDAARP ARRRRGPKER EDEKGGRREE LHVASDKRGR
250 260 270 280 290 300
RKGKGKGATR VAAAAVASKH GFERPTAPVV REVALPETLT VGELAQKLAI KAPELIKSLM
310 320 330 340 350 360
GMGVMATINQ AIDRDTATLV VEELGHVAVP MQVEDLDEEL AVATAEPVGE LKPRPPVVTI
370 380 390 400 410 420
MGHVDHGKTS LLDYIRSSRV ASGEAGGITQ HIGAYHVQTN RGGITFLDTP GHAAFTAMRA
430 440 450 460 470 480
RGAKVTDIVI LVVSADDGVM PQTIEAVQHA KAAGVPMVVA VNKIDKPEAD PDRVKNELSV
490 500 510 520 530 540
HQVIPEEWGG DTQFIHVSAL KGTGVEDLLE AVNLQAEVME LKAPVEGPAA GVVIESRLDK
550 560 570 580 590 600
GRGPVATVLV QRGTLNKGDV ILTGQEFGRV RAMFDENGKP VKSAGPSMPV EVLGLSGTPN
610 620 630 640 650 660
AGDDVLVLED ERKAREVALF RQGKFRESKL ATQQAAKLEN LFSQMQEGQV GTVNILLKAD
670 680 690 700 710 720
VQGSAEAIRD ALEKLSTDEV KVKIIAAGVG GITESDINLA KASEAIVIGF NVRADAGARK
730 740 750 760 770 780
AVAEQEVDLR YYSVIYEAID DVRQALTGLL SPEMREEIIG LAQVKDVFKS SQFGAVAGCL
790 800 810 820 830 840
VVEGTIKRGN PIRVLRNNVV IYEGELESLR RFKDDVNEVR AGTDCGIAVK NYNDVKPGDQ
850
IEVYQRVEVA RTL