B8G242
Gene name |
cobQ |
Protein name |
Cobyric acid synthase |
Names |
|
Species |
Desulfitobacterium hafniense (strain DSM 10664 / DCB-2) |
KEGG Pathway |
dhd:Dhaf_1304 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B8G242
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B8G242-F1 | Predicted | AlphaFoldDB |
No variants for B8G242
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B8G242 | |||||
No associated diseases with B8G242
4 regional properties for B8G242
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CobQ/CobB/MinD/ParA nucleotide binding domain | 10 - 241 | IPR002586 |
| domain | CobB/CobQ-like glutamine amidotransferase | 265 - 455 | IPR011698 |
| domain | Cobyric acid synthase, glutamine amidotransferase type 1 | 266 - 462 | IPR033949 |
| domain | Cobyric acid synthase, N-terminal domain | 10 - 231 | IPR047045 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ABC-type vitamin B12 transporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin. |
| catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cobalamin biosynthetic process | The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
| glutamine metabolic process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGKKAAARL | MIQGTSSNVG | KSVLAAAFCR | IFYQEGYHVA | PFKAQNMALN | SFITRSGGEM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GRAQVVQAQA | AGLEPDVRMN | PVLLKPTGHT | GSQVIVLGKA | QGTLSALKYH | GDYQRKTWPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VEEALHELLE | EHEIVVIEGA | GSPAEVNLKQ | NDIVNMRVAK | EAQAPVLLVA | DIDRGGALAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VVGTLELLEP | EERQLVQGIV | MNKFRGDIKL | LQPALDFLEE | RTGIPVVGVV | PFYDQFKIPE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EDSVVLEEQN | TSKRDQGKSR | DEALDVAVIR | LPYLSNFTDF | DPFEDEPDVI | LRYVREPSEL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GEPDCVIIPG | SKNTLSDLRF | LWESGLGEKI | IKFWQEDVPI | IGICGGYQML | GRIVRDPLGT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ESDLKEIAGL | GILPMETEFE | LDKHTVQSRG | KVVGGELFLA | RCQGTEITGY | EIHMGRSQGE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GHSLFEIEAQ | ETAYGDGMSA | GSAVGTYLHG | IFDNDPLRTA | LLEWLWERRG | GTRPVGETMS |
| 490 | 500 | 510 | |||
| QAAIREQSFN | ELADWVRNSM | DMEKIRAMMG | LHKG |