B8FJL5

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Desulfatibacillum aliphaticivorans
KEGG Pathway
dal:Dalk_3998
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

774-889 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8FJL5

Entry ID Method Resolution Chain Position Source
AF-B8FJL5-F1 Predicted AlphaFoldDB

No variants for B8FJL5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8FJL5

No associated diseases with B8FJL5

5 regional properties for B8FJL5

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 615 - 807 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 7 - 117 IPR007695
domain DNA mismatch repair protein MutS, core 274 - 597 IPR007696
domain DNA mismatch repair protein MutS, connector domain 127 - 257 IPR007860
domain DNA mismatch repair protein MutS, clamp 434 - 525 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAPKVTPMV RQYLSIKAEH PDSILFFRMG DFYEMFFEDA EKASKALDIT LTSRNKNDPD
70 80 90 100 110 120
PVPMCGVPHH SANGYVARLV EQGFKVAICD QVQDPSEAKG LVERKVVQVV TPGMQLDGRY
130 140 150 160 170 180
LDASQNNFVC AAVTGRGGVG LAFLDISTGA FLVTQVTTPE SAFQEILRMG PKELVLPEKF
190 200 210 220 230 240
EENARAAAAM RMADQLPTSR LEGKDFENAR TRDRLLEHFK TRSLEGFGIQ DLPLAVRAAG
250 260 270 280 290 300
ALLHYVQQAQ RQEITHVTKI QAYFQDQFLW IDDNSARNLE LLKNIRNGTR QGALISVLDK
310 320 330 340 350 360
TVTAMGARLM SYLLRYPLID PQVINLRLDA VEQAKDLARV RDEVREALKE VHDLERLRSR
370 380 390 400 410 420
TALGHANGRD LAAMGESLKQ LPRLWALLKE NFESPLLCGE ATDDGLTDVA DLIDRSIRED
430 440 450 460 470 480
APPGVRDGGM IKPGFNEELD EVAALATDVK GLIAGLEAQE KERTGISTLK VRYNKVFGYY
490 500 510 520 530 540
IEISKNQTKS IPPHYVRKQT LVNAERYITD ELKEFETKVL GAEERRVALE YNIFTQIVDR
550 560 570 580 590 600
INGENDRLEK ASHLIAWVDV LAALGHVADH NGYCRPVVDM GQTLDLQESR HPVVEKMLPG
610 620 630 640 650 660
QRFVPNNIAM NNLDQQILMI TGPNMAGKST VLRQAALCVI MAQMGSFVPA EKAVVGVVDK
670 680 690 700 710 720
IFTRVGALDN LSQGESTFMV EMQETANILN NVSHRSLVIL DEIGRGTSTF DGLSIAWAVA
730 740 750 760 770 780
EYLHDYKDHG VKTMFATHYH ELTDLTKTHP RVKNFNIAVN EWNDEIIFLH SLVEGGTNKS
790 800 810 820 830 840
YGIQVARLAG IPASVIRRSK QVLQTIEDSE EARVAYSAKA SGKSGKKDVQ VQMSLFPTPG
850 860 870 880
ELAAQALERM DINVMTPLEA MNVLSELQQR VKRPEKAPAD VTAETEDQE