B8E1B4

PR
Gene name
tsaD
Protein name
tRNA N6-adenosine threonylcarbamoyltransferase
Names
N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Species
Dictyoglomus turgidum (strain DSM 6724 / Z-1310)
KEGG Pathway
dtu:Dtur_0962
EC number
2.3.1.234: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

192-261 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8E1B4

Entry ID Method Resolution Chain Position Source
AF-B8E1B4-F1 Predicted AlphaFoldDB

No variants for B8E1B4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8E1B4

No associated diseases with B8E1B4

2 regional properties for B8E1B4

Type Name Position InterPro Accession
domain Gcp-like domain 1 - 329 IPR000905
conserved_site Peptidase M22, conserved site 96 - 116 IPR017860

Functions

Description
EC Number 2.3.1.234 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
iron ion binding Binding to an iron (Fe) ion.
N(6)-L-threonylcarbamoyladenine synthase activity Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.

1 GO annotations of biological process

Name Definition
tRNA threonylcarbamoyladenosine modification The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITIGIETSC DETSVSLLED GNKILSNLVS SQVEIHKTFG GVVPEVASRI HVEVLNRLIE
70 80 90 100 110 120
LALEKAKKEF TDIDLIAVTQ GPGLIGALWI GIMAAKTLSL ALNKPLIGVN HLEGHIFANF
130 140 150 160 170 180
LGEDPPTFPF IALIVSGGHT EYILVEDIGV YKILGQTLDD AAGEAFDKVA RILGLNYPGG
190 200 210 220 230 240
PEIDKISKMG KPIFNFPKIK CDRELDISFS GIKTAVLYLV RDLKKEGKEI PVADIAASFQ
250 260 270 280 290 300
ERVVEELLER AFLALNKFNI KTLVVSGGVA SNSYLQRRFK EESRKEGIKL YIPPPYLCTD
310 320 330
NGAMIACAGY HLYQKGYKSD LYLSANPDLL LGER