B8DTW3

PR
Gene name
carB
Protein name
Carbamoyl-phosphate synthase large chain
Names
Carbamoyl-phosphate synthetase ammonia chain
Species
Bifidobacterium animalis subsp lactis (strain AD011)
KEGG Pathway
bla:BLA_1154
EC number
6.3.4.16: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

101-170 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8DTW3

Entry ID Method Resolution Chain Position Source
AF-B8DTW3-F1 Predicted AlphaFoldDB

No variants for B8DTW3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8DTW3

No associated diseases with B8DTW3

3 regional properties for B8DTW3

Type Name Position InterPro Accession
domain CASTOR, ACT domain 72 - 140 IPR027795-1
domain CASTOR, ACT domain 262 - 322 IPR027795-2
domain CASTOR1, N-terminal 9 - 69 IPR040778

Functions

Description
EC Number 6.3.4.16 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKRTDIKSV MVIGSGPIVI GQAAEFDYSG TQACRVLREE GVRVILVNSN PATIMTDPEM
70 80 90 100 110 120
ADATYIDPIS TPILEKIIAK ERPDALLPTL GGQTALNAAV ALGEAGVLKK YNVELIGASL
130 140 150 160 170 180
EAIDRGEDRE SFKKVVKEAG AESARSDIAH TLEEVDAIAE RFGFPLVVRP SFTMGGLGSG
190 200 210 220 230 240
IAHDTEELHR IAGAGIHYSP TDEVLIEEGI EGWKEYELEL MRDRNDNVVV VCPIENVDPV
250 260 270 280 290 300
GVHTGDSITV APVFTLTDRE YQKLRDIGIA IIRGVGVDTG GCNIQFAIHP DTGRIIVIEM
310 320 330 340 350 360
NPRVSRSSAL ASKATGFPIA KIATKLALGY TLDEIQNDIT RSTPASFEPT IDYVVTKVPR
370 380 390 400 410 420
FAFEKFPGAD PTLTTSMKSV GEAMALAGNF QESLGKAMRS IDKRHMGFSW DGEKPSEGEV
430 440 450 460 470 480
HELLEQMRIP TEHRYLQVMR AIWGGATPEQ IFNATKIDPW FIDQFFQINA TAMQVRGAET
490 500 510 520 530 540
LSKRLLRKAK LAGLSDVQIA HLRRLGDEGE NTIRELRWNY GLHPVFKTVD TCAAEFAAQT
550 560 570 580 590 600
PYYYSCYADE TELRKREREA VIILGSGPNR IGQGIEFDYT CVHAVQELGK DYDTIMVNCN
610 620 630 640 650 660
PETVSTDYDM SDRLYFEPLT FEDVLEIYEA EKKQGPIKGV IVQLGGQTPL SLAARLKAAG
670 680 690 700 710 720
VPILGTTPEA IDLAENRELF GEVLRQEHLN APRFGTALSL EEAREAAHNI GYPVLVRPSY
730 740 750 760 770 780
VLGGRGMEIV YDDAQLETYV NRALSEAKAD TVVSGRLPSP LLIDKFLQDA IEIDVDALFD
790 800 810 820 830 840
GEELYIGGIM EHIEEAGVHS GDAACTLPPS TLSDDQIRRL REATLAIAKG CQVRGLMNVQ
850 860 870 880 890 900
YAFMANTLYV IEANPRASRT VPFASKATGV ALAKAAARIM AGETIEQQRE NGLLLPYGDG
910 920 930 940 950 960
GDVRLGQQVA VKESVLPFKR FRTPVGKTVD ILLGPEMRST GEVMGFDRDF PHAFAKSQLA
970 980 990 1000 1010 1020
SYEGGLPTNG NVFISVNDTD KRQLPLFAVR LVELGFEIWA TEGTASVLRR YGIESKIVDK
1030 1040 1050 1060 1070 1080
IHSRVDTDPE HPIEIQHAAG SVGKNVVELI EEGQIDLILN TPNSRGSRSD GYSIRAAAIA
1090 1100 1110 1120 1130
ADIPQYTTMT EFSAVLLAIE AVKKNDYEVM SIQEHSRELY ELERKHKEEG EEARAQ