B8DHH5

PR
Gene name
accA
Protein name
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Names
ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha
Species
Listeria monocytogenes serotype 4a (strain HCC23)
KEGG Pathway
lmh:LMHCC_0996
EC number
2.1.3.15: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8DHH5

Entry ID Method Resolution Chain Position Source
AF-B8DHH5-F1 Predicted AlphaFoldDB

No variants for B8DHH5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8DHH5

No associated diseases with B8DHH5

1 regional properties for B8DHH5

Type Name Position InterPro Accession
domain Acetyl-coenzyme A carboxyltransferase, C-terminal 31 - 292 IPR011763

Functions

Description
EC Number 2.1.3.15 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.

3 GO annotations of molecular function

Name Definition
acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carboxyl- or carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).

2 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
malonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANEMEFEKP ILELKSKIAD LKEYNETSDV DLTNEIEKLE KRLGKLESSI YSNMTAWDKF
70 80 90 100 110 120
QVARHPERPT TLDYISLLFE DFMELHGDRA FGDDAAIVGG IATFKGVPVT VIGHQRGKDT
130 140 150 160 170 180
KDNLHRNFGM PHPEGFRKAL RLMKQADKFG RPIICFIDTK GAYPGRAAEE RGQSEAIARN
190 200 210 220 230 240
LYEMSDMKVP IISIVIGEGG SGGALALGVG NQIFMLENAV FSVISPEGAA AILWKDASQA
250 260 270 280 290 300
KKAAESMRIT AGDLFELGIT DGIIPEVKGG AHRDLNAQAE EINKTITKSL HALMAFSEEQ
310
LIEQRYEKFK KIGVYDTL