B8D0C7

PR
Gene name
rplB
Protein name
50S ribosomal protein L2
Names
Species
Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)
KEGG Pathway
hor:Hore_01200
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-79 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8D0C7

Entry ID Method Resolution Chain Position Source
AF-B8D0C7-F1 Predicted AlphaFoldDB

No variants for B8D0C7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8D0C7

No associated diseases with B8D0C7

3 regional properties for B8D0C7

Type Name Position InterPro Accession
domain Ribosomal Proteins L2, RNA binding domain 42 - 117 IPR022666
domain Ribosomal protein L2, C-terminal 124 - 252 IPR022669
conserved_site Ribosomal protein L2, conserved site 218 - 229 IPR022671

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
large ribosomal subunit The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).

3 GO annotations of molecular function

Name Definition
rRNA binding Binding to a ribosomal RNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAIKKFKPTT PSRRFMTVSA FDEITRREPE KSLLAPLKKT GGRNSYGRVT VRHRGGGHKR
70 80 90 100 110 120
RYRIIDFKRD KDGVPARVAS IEYDPNRSAR IALLHYVDGE KRYILAPNKL QVGDTVKSGE
130 140 150 160 170 180
DAEIKPGNAL KLKNIPVGTI IHNIELKPGK GGQLARAAGT MAQILAKEGK YAHIKLPSGE
190 200 210 220 230 240
VRLISLECKA TIGQVGNIDH ENISIGKAGR KRWLGKRPHV RGVAMNPVDH PHGGGEGRTS
250 260 270
TGRHPVTPWG KRTLGKKTRK RKASDKYIIR SRRARKR