B8CKH5

PR
Gene name
truB
Protein name
tRNA pseudouridine synthase B
Names
tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase
Species
Shewanella piezotolerans (strain WP3 / JCM 13877)
KEGG Pathway
swp:swp_1220
EC number
5.4.99.25: Transferring other groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

55-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B8CKH5

Entry ID Method Resolution Chain Position Source
AF-B8CKH5-F1 Predicted AlphaFoldDB

No variants for B8CKH5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B8CKH5

No associated diseases with B8CKH5

3 regional properties for B8CKH5

Type Name Position InterPro Accession
domain Pseudouridine synthase II, N-terminal 32 - 179 IPR002501
domain tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal 252 - 308 IPR015240
domain tRNA pseudouridylate synthase B, C-terminal 180 - 247 IPR032819

Functions

Description
EC Number 5.4.99.25 Transferring other groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
tRNA pseudouridine synthase activity Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.

1 GO annotations of biological process

Name Definition
tRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARRSRGRHI DGVLLLDKDT GMSSNFALQR VKRFFNANKA GHTGALDPLA TGMLPICLGE
70 80 90 100 110 120
ATKFSQHLLD ADKRYLVTAK LGQRTDTSDS DGEVVQTREI DFTQEQLDTA LEYFRGKTMQ
130 140 150 160 170 180
VPSMYSALKY QGQPLYKYAR EGIEVPREAR PINVFELNFI SLEGDELTLD IHCSKGTYIR
190 200 210 220 230 240
TITDDLGEML GCGAHVIMLR RTQVAGYPYD NMVSLAELEA LVTKVEAESL TLAEVLDPLL
250 260 270 280 290 300
LPMDTAVSDF KEINVSDDIA PFLMNGNPVQ VANLPVDELV RITLGVERRF VGIGQMNDDG
310
LLAPKRLIVL RDEAAQ