Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B8AMA8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B8AMA8-F1 | Predicted | AlphaFoldDB |
No variants for B8AMA8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B8AMA8 | |||||
No associated diseases with B8AMA8
5 regional properties for B8AMA8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, PHD-type | 190 - 238 | IPR001965 |
| conserved_site | Zinc finger, PHD-type, conserved site | 191 - 237 | IPR019786 |
| domain | Zinc finger, PHD-finger | 188 - 240 | IPR019787 |
| domain | Alfin, N-terminal | 15 - 140 | IPR021998 |
| domain | Alfin1-like, PHD finger | 190 - 238 | IPR044104 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| histone binding | Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEMAPAAQVA | SNPRTVEDIF | KDYSARRGAL | VRALTSDVDE | FFGLCDPDKE | NLCLYGLANG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SWEVALPAEE | VPPELPEPAL | GINFARDGMN | RRDWLSLVAV | HSDSWLVSVA | FFFAARLNGN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ERKRLFNMIN | DLPTVYEALV | DRKHVRDRSG | VDSSGKSKHS | TKRTGEGQVK | RSRVVAEEYE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DDDEEHNETF | CGTCGGLYNA | NEFWIGCDIC | ERWFHGKCVR | ITPAKAEHIK | HYKCPDCSSS |
| SSKKTRL |