B7XHR6

PR
Gene name
KIN1 (EBI_21713)
Protein name
Probable serine/threonine-protein kinase KIN1 homolog
Names
Species
Enterocytozoon bieneusi (strain H348) (Microsporidian parasite)
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-72 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B7XHR6

Entry ID Method Resolution Chain Position Source
AF-B7XHR6-F1 Predicted AlphaFoldDB

No variants for B7XHR6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B7XHR6

No associated diseases with B7XHR6

2 regional properties for B7XHR6

Type Name Position InterPro Accession
domain Protein kinase domain 67 - 316 IPR000719
active_site Serine/threonine-protein kinase, active site 184 - 196 IPR008271

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
exocytosis A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQSTSKYNCD SDYIAGRNYN TKRTNGREEL STGLTNEETG VVNISDENNI FFKKNIDYVK
70 80 90 100 110 120
GSRIGKYKLI KTLGKGSCAK VVQAEDCETG EYVAIKIIER TPKQLSDIRI YREALICSLF
130 140 150 160 170 180
NHPHIIKLLD FFHTTEYFFL IFEYVDGQQL YDIILNKGYL DEDEARKYFR QIISAVDYSH
190 200 210 220 230 240
RNSVVHRDLK IENILIDRND NIKLIDFGLS NFYDADDLLG TFCGSLYFAA PELLLGTRYT
250 260 270 280 290 300
GPEIDVWSLG VILYVMLVGK VPFDDENIHA LQNKIKSCKF KFEKTISPEA QDLITNMILS
310 320 330 340 350 360
SDARINLENV KKSKWTNLGY KNLTNNFMTL RKPIIEINKN ILRALQAAMF FQFTDMERVL
370 380 390 400 410 420
MQYLQICKGD KHSLEQTYWC KKPVVILYYL TMEKFNELNY KSIPIDIDTG MNTKSLIDIT
430 440 450 460 470 480
IEKQPIIIYN FVRFTNAKKN NNPYNLFFSR SVFEPEMEFL NMTKDVSLDS CNISEDENKK
490 500 510 520 530 540
HNFPKIKQSI IKGLFKGIKI KNGDKDYVKN AIIKILLDLD ITYEANEKSY FCSYSHSGVE
550 560 570 580 590
CHFKIDLYFN ILLLEHYVVL NCLNRKKDNF KLVTELIKEK LEEIGDTSNY PENAI