B7N829
Gene name |
dgt |
Protein name |
Deoxyguanosinetriphosphate triphosphohydrolase |
Names |
dGTP triphosphohydrolase, dGTPase |
Species |
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) |
KEGG Pathway |
eum:ECUMN_0158 |
EC number |
3.1.5.1: Triphosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B7N829
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B7N829-F1 | Predicted | AlphaFoldDB |
No variants for B7N829
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B7N829 | |||||
No associated diseases with B7N829
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.5.1 | Triphosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| dGTPase activity | Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| dGTP catabolic process | The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAQIDFRKKI | NWHRRYRSPQ | GVKTEHEILR | IFESDRGRII | NSPAIRRLQQ | KTQVFPLERN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AAVRTRLTHS | MEVQQVGRYI | AKEILSRLKE | LKLLEAYGLD | ELTGPFESIV | EMSCLMHDIG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NPPFGHFGEA | AINDWFRQRL | HPEDAESQPL | TDDRCSVAAL | RLRDGEEPLN | ELRRKIRQDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CHFEGNAQGI | RLVHTLMRMN | LTWAQVGGIL | KYTRPAWWRG | ETPETHHYLM | KKPGYYLSEE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AYIARLRKEL | NLALYSRFPL | TWIMEAADDI | SYCVADLEDA | VEKRIFTVEQ | LYHHLHEAWG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QHEKGSLFSL | VVENAWEKSR | SNSLSRSTED | QFFMYLRVNT | LNKLVPYAAQ | RFIDNLPAIF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AGTFNHALLE | DASECSDLLK | LYKNVAVKHV | FSHPDVEQLE | LQGYRVISGL | LEIYRPLLSL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SLSDFTELVE | KERVKRFPIE | SRLFNKLSTR | HRLAYVEAVS | KLPSDSPEFP | LWEYYYRCRL |
| 490 | 500 | ||||
| LQDYISGMTD | LYAWDEYRRL | MAVEQ |